DRSC/TRiP Functional Genomics Resources

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Protein Alignment jet and Fbxl6

DIOPT Version :9

Sequence 1:NP_608880.2 Gene:jet / 33705 FlyBaseID:FBgn0031652 Length:319 Species:Drosophila melanogaster
Sequence 2:NP_038937.2 Gene:Fbxl6 / 30840 MGIID:1354705 Length:535 Species:Mus musculus


Alignment Length:388 Identity:81/388 - (20%)
Similarity:134/388 - (34%) Gaps:115/388 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 PEEEAHLMA-------MASGGQPTRTASPRPLVTASIAAPR---SL---FDVCWDDVLIPQVAVY 57
            |...||..|       :|.|  ||..|.||       ..||   ||   .|..|.|.:..:|.|:
Mouse    59 PRARAHRRARRRAPRSLARG--PTAVAKPR-------TKPRPEPSLDQGLDSGWGDRIPLEVLVH 114

  Fly    58 LSLKDLFNLRCCSRTAQRFVEAALEKRQELHLSGNNTK---NIDVAFRVLARCCQ---RLEVLHL 116
                 :|.|...:.....|:..|....:..|.:.::..   .:.::..::.|..:   :.|...|
Mouse   115 -----IFGLLVAAHGPMPFLGRAARVCRHWHEATSHPSLWHTVTLSPSLVGRAGKGNLKGEKKLL 174

  Fly   117 ACCRWLTD------------------ELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKE 163
            ||..||..                  ..:|.|::....||..:.|::|..:||.:|..:...|.:
Mouse   175 ACLEWLVPNRFSQLQSLTLIHWKSQVHSVLELVSKFCPRLTFLKLSDCHTVTAETLVMLARACCQ 239

  Fly   164 LRVLKLSKCQWLTTGAVDALTLHQSKLVEFDISY-------CGAIGERCLIIFFRKLNKLTVLSL 221
            |..|.|......:|..|..|....|::.:..::|       .||:.:.|       ..:|.||.:
Mouse   240 LHSLDLHHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLDNC-------CPQLQVLQV 297

  Fly   222 A------NTPSVTDQVLIQIGNYCRELEHINVIG------------------------------C 250
            :      |||.......:|.|  |.:|:.:.::.                              |
Mouse   298 STGMNCNNTPLQLPVEALQKG--CPQLQVLRLLNLIWLPKPCGRGVPQGPGFPSLEELCLAGSTC 360

  Fly   251 AAISDYGVHALTVHCLRLRTLLIRRCPRVTELSLAPL---RQRRLYIDRPQPDVGLNAYNLND 310
            ..:|:..:..|.....:||.|.:|.|.|||...|..|   ...:||         |..|.::|
Mouse   361 NFVSNEVLGRLLHRSPKLRMLDLRGCARVTPSGLCHLPCQELEQLY---------LGLYGISD 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jetNP_608880.2 leucine-rich repeat 85..110 CDD:275381 2/30 (7%)
AMN1 96..>261 CDD:187754 40/228 (18%)
leucine-rich repeat 111..137 CDD:275381 8/43 (19%)
leucine-rich repeat 138..163 CDD:275381 7/24 (29%)
leucine-rich repeat 164..189 CDD:275381 6/24 (25%)
leucine-rich repeat 190..215 CDD:275381 4/31 (13%)
leucine-rich repeat 216..241 CDD:275381 9/30 (30%)
leucine-rich repeat 242..267 CDD:275381 4/54 (7%)
leucine-rich repeat 268..290 CDD:275381 10/24 (42%)
Fbxl6NP_038937.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..25
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 61..99 14/46 (30%)
F-box-like 105..155 CDD:289689 8/54 (15%)
LRR 1 169..195 6/25 (24%)
AMN1 171..390 CDD:187754 45/227 (20%)
leucine-rich repeat 188..213 CDD:275381 2/24 (8%)
LRR 2 196..221 5/24 (21%)
leucine-rich repeat 214..239 CDD:275381 7/24 (29%)
LRR 3 222..247 8/24 (33%)
leucine-rich repeat 240..291 CDD:275381 11/57 (19%)
LRR 4 273..299 7/32 (22%)
leucine-rich repeat 292..321 CDD:275381 9/30 (30%)
LRR 5 304..329 7/26 (27%)
leucine-rich repeat 322..349 CDD:275381 1/26 (4%)
LRR 6 330..357 0/26 (0%)
AMN1 <349..500 CDD:187754 18/75 (24%)
leucine-rich repeat 350..377 CDD:275381 3/26 (12%)
LRR 7 360..385 6/24 (25%)
leucine-rich repeat 378..401 CDD:275381 10/22 (45%)
LRR 8 386..411 9/33 (27%)
LRR 9 415..441 81/388 (21%)
leucine-rich repeat 434..466 CDD:275381
leucine-rich repeat 467..491 CDD:275381
LRR 10 474..499
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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