DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jet and Fbxl21

DIOPT Version :9

Sequence 1:	NP_608880.2	Gene:	jet / 33705	FlyBaseID:	FBgn0031652	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_038951543.1	Gene:	Fbxl21 / 306750	RGDID:	1305555	Length:	460	Species:	Rattus norvegicus

Alignment Length:	227	Identity:	56/227 - (24%)
Similarity:	83/227 - (36%)	Gaps:	77/227 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 CQRLEVLHLACCRWLTDELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKELRVLKLSKC 172
            ||.|..|.|. ...|:|||||.|.:...     ||| |.:.|..:|..|     .:::...:.|.
  Rat   255 CQGLRELALN-YYILSDELLLALSSETH-----VNL-EHLRIDVVSENP-----GQIKFHSIKKP 307

  Fly   173 QWLTTGAVDALTLHQSKL----------VEFDISY-------------------CGAIGERCLII 208
            .|      |||..|...:          .|||..:                   .|.||..|
  Rat   308 SW------DALVKHSPGVNVVMYFFLYEEEFDTFFKEETPVTHLYFGRSVSRTILGRIGLNC--- 363

  Fly   209 FFRKLNKLTVLSLANTPSVTDQVLIQIGNYCRELEHINV----IGCAAISDYGVHALTVHCLRLR 269
              .:|.:|.|  .||.....|..||:|..:|:.|..:.:    :.|:|..::
  Rat   364 --PRLIELVV--CANGLQPLDSELIRIAEHCKNLTALGLSECEVSCSAFVEF------------- 411

  Fly   270 TLLIRRC-PRVTELSLAPLRQRRLYIDRPQPD 300
               :|.| .|:|:|||  :.:..:..||..||
  Rat   412 ---VRLCGRRLTQLSL--MEEVLVPDDRYTPD 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jet	NP_608880.2	leucine-rich repeat	85..110	CDD:275381	1/1 (100%)
		AMN1	96..>261	CDD:187754	45/185 (24%)
		leucine-rich repeat	111..137	CDD:275381	10/25 (40%)
		leucine-rich repeat	138..163	CDD:275381	7/24 (29%)
		leucine-rich repeat	164..189	CDD:275381	6/24 (25%)
		leucine-rich repeat	190..215	CDD:275381	8/53 (15%)
		leucine-rich repeat	216..241	CDD:275381	9/24 (38%)
		leucine-rich repeat	242..267	CDD:275381	3/28 (11%)
		leucine-rich repeat	268..290	CDD:275381	7/22 (32%)
Fbxl21	XP_038951543.1	F-box-like	68..111	CDD:403981
		leucine-rich repeat	206..231	CDD:275381
		leucine-rich repeat	232..257	CDD:275381	1/1 (100%)
		leucine-rich repeat	258..283	CDD:275381	10/30 (33%)
		leucine-rich repeat	284..318	CDD:275381	11/45 (24%)
		leucine-rich repeat	329..365	CDD:275381	7/40 (18%)
		AMN1	<359..>424	CDD:187754	21/87 (24%)
		leucine-rich repeat	366..392	CDD:275381	10/27 (37%)
		leucine-rich repeat	393..418	CDD:275381	5/40 (13%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900