DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment jet and Fbxo39

DIOPT Version :9

Sequence 1:	NP_608880.2	Gene:	jet / 33705	FlyBaseID:	FBgn0031652	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001034107.1	Gene:	Fbxo39 / 303287	RGDID:	1311464	Length:	443	Species:	Rattus norvegicus

Alignment Length:	261	Identity:	52/261 - (19%)
Similarity:	93/261 - (35%)	Gaps:	64/261 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 VAVYLSLKDLFNLRCCSRTAQRFVEAALEKRQELHLSGNNTKNIDVAFRVLARCCQRLEVLHLAC 118
            ||..|:::|.|:.......:.:|.:|    ....|         ::.|..|...|
  Rat   194 VASELNIEDFFSHHLAVYGSSQFNKA----MATFH---------NLTFLTLNYNC---------- 235

  Fly   119 CRWLTDELLLPLLANNKKRLWAVNLNECVN------ITALSLQPIIVECKEL-------RVLKLS 170
               ::||||..|..||...|..:|:...|:      :..:|...:..:...|       ||:|..
  Rat   236 ---ISDELLETLSENNAGTLRTMNIKCHVHDPHGQVVWGMSWAKLARQASNLKVNFFFERVMKYE 297

  Fly   171 KCQ--WLTTGAVDALTLHQSKLVEFDISYCGAIGERCLIIFFRK-LNKLTVLSLANTPSVTDQVL 232
            :..  .|....|.:::|......:.|.|....:.:  |:..||. |.|||.....|..|:.:|:
  Rat   298 RLARILLQEIPVRSISLRSCYFSDPDWSMRPTLTD--LLPTFRNTLQKLTFEFNNNHESLDEQL- 359

  Fly   233 IQIGNYCRELEHINVIGCAAISDYGVHALTVHCLRLRTLLIRRCPRVTELSLAPLR--QRRLYID 295
                       |:.::.|..:..:.:.|.      |....:.|..:..|.....||  :.|:|.:
  Rat   360 -----------HLLILACRKLFYFKIWAF------LDVKFVERILKSQEEGQCSLRTLKVRIYTN 407

  Fly   296 R 296
            |
  Rat   408 R 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jet	NP_608880.2	leucine-rich repeat	85..110	CDD:275381	4/24 (17%)
		AMN1	96..>261	CDD:187754	35/180 (19%)
		leucine-rich repeat	111..137	CDD:275381	7/25 (28%)
		leucine-rich repeat	138..163	CDD:275381	4/30 (13%)
		leucine-rich repeat	164..189	CDD:275381	7/33 (21%)
		leucine-rich repeat	190..215	CDD:275381	6/25 (24%)
		leucine-rich repeat	216..241	CDD:275381	5/24 (21%)
		leucine-rich repeat	242..267	CDD:275381	3/24 (13%)
		leucine-rich repeat	268..290	CDD:275381	5/23 (22%)
Fbxo39	NP_001034107.1	F-box-like	16..57	CDD:403981
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900