DRSC/TRiP Functional Genomics Resources

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Protein Alignment jet and FBXL2

DIOPT Version :9

Sequence 1:NP_608880.2 Gene:jet / 33705 FlyBaseID:FBgn0031652 Length:319 Species:Drosophila melanogaster
Sequence 2:NP_001336245.1 Gene:FBXL2 / 25827 HGNCID:13598 Length:454 Species:Homo sapiens


Alignment Length:261 Identity:68/261 - (26%)
Similarity:107/261 - (40%) Gaps:34/261 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 SLKDLFNLRCCSRTAQRFVEAALEKRQELHLSGNNTKNID-----------VAFRVLARCCQRLE 112
            |..|:..|..|::.::.:        ..|.|.|:|.:.||           |...:..||...|.
Human    25 SFLDIVTLCRCAQISKAW--------NILALDGSNWQRIDLFNFQTDVEGRVVENISKRCGGFLR 81

  Fly   113 VLHLACCRWLTDELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKELRVLKLSKCQWLTT 177
            .|.|..|..:.|. .|...|.|.:.:..:|||.|..||..:...:...|.:|:.|.|:.|..:|.
Human    82 KLSLRGCIGVGDS-SLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITN 145

  Fly   178 GAVDALTLHQSKLVEFDISYCGAIGERCLIIFFRKLNKLTVLSLANTPSVTDQVLIQIGNYCREL 242
            .::..::.....|...::|:|..|.:..:....|....|..|.|.....:.|:.|..|.|||.||
Human   146 SSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHEL 210

  Fly   243 EHINVIGCAAISDYGVHALTVHCLRLRTLLIRRCPRVTELSLAPLRQRRLYIDRPQPDVGLNAYN 307
            ..:|:..|:.|:|.||..:...|.||:.|.:..|..:|:.||..|              |||...
Human   211 VSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTAL--------------GLNCPR 261

  Fly   308 L 308
            |
Human   262 L 262

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jetNP_608880.2 leucine-rich repeat 85..110 CDD:275381 9/35 (26%)
AMN1 96..>261 CDD:187754 47/175 (27%)
leucine-rich repeat 111..137 CDD:275381 8/25 (32%)
leucine-rich repeat 138..163 CDD:275381 7/24 (29%)
leucine-rich repeat 164..189 CDD:275381 5/24 (21%)
leucine-rich repeat 190..215 CDD:275381 5/24 (21%)
leucine-rich repeat 216..241 CDD:275381 9/24 (38%)
leucine-rich repeat 242..267 CDD:275381 8/24 (33%)
leucine-rich repeat 268..290 CDD:275381 7/21 (33%)
FBXL2NP_001336245.1 F-box-like 15..56 CDD:315592 8/38 (21%)
leucine-rich repeat 52..79 CDD:275381 5/26 (19%)
AMN1 <76..223 CDD:332986 40/147 (27%)
leucine-rich repeat 80..99 CDD:275381 6/19 (32%)
leucine-rich repeat 106..131 CDD:275381 7/24 (29%)
leucine-rich repeat 132..157 CDD:275381 5/24 (21%)
leucine-rich repeat 158..183 CDD:275381 5/24 (21%)
AMN1 168..398 CDD:332986 32/109 (29%)
leucine-rich repeat 184..209 CDD:275381 9/24 (38%)
leucine-rich repeat 210..235 CDD:275381 8/24 (33%)
leucine-rich repeat 236..261 CDD:275381 10/38 (26%)
leucine-rich repeat 262..287 CDD:275381 1/1 (100%)
leucine-rich repeat 288..313 CDD:275381
leucine-rich repeat 314..364 CDD:275381
leucine-rich repeat 374..393 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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