DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment jet and Lrrc29

DIOPT Version :9

Sequence 1:NP_608880.2 Gene:jet / 33705 FlyBaseID:FBgn0031652 Length:319 Species:Drosophila melanogaster
Sequence 2:NP_001355337.1 Gene:Lrrc29 / 234684 MGIID:2443262 Length:621 Species:Mus musculus


Alignment Length:291 Identity:70/291 - (24%)
Similarity:114/291 - (39%) Gaps:83/291 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 YLSLKDLFNLRCCSRTAQRFVE---AALEKRQELHLSGNNTKNIDVAFRVLARCC---------- 108
            :||||.|          ||..:   |||...:||       :::|     :|.||          
Mouse   308 HLSLKKL----------QRLTDAGCAALGALREL-------QSLD-----MAECCLVSGRELAQV 350

  Fly   109 --------QRLEVLHLACCRWLTDELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKELR 165
                    :.|..|.||.|..|.|..:|.::......|..::|:.|:.:|..::|.|......|.
Mouse   351 LGSVRRAPRALTSLRLAYCSSLKDASVLSMIPALGPSLKVLDLSSCMALTNQTMQAICTYLIHLS 415

  Fly   166 VLKLSKCQ----WLTTG-------AVDALTLHQ------------------------SKLVEFDI 195
            ||:|:.|:    |...|       .|.:..|||                        ..|.|.|:
Mouse   416 VLRLAWCKELQDWGLLGLKEPSDEPVLSPQLHQKVDNEAPDPQEPSSEPQGSSLLMLQALQELDL 480

  Fly   196 SYCGAIGERCL--IIFFRKLNKLTVLSLANTPSVTDQVLIQIGNYCRELEHINVIGCAAISDYGV 258
            :.|..:.:..|  ::.|.:|.:   |||:..|:.||..|:.:...|..||.:.:..|:.:||.|.
Mouse   481 TACSKLTDASLAKVLQFPQLRQ---LSLSLLPAFTDTGLVAVARGCPSLERLTLSHCSHLSDEGW 542

  Fly   259 HALTVHCLRLRTLLIRRCPRVTELSLAPLRQ 289
            ........||:.|.:..|.::||.:|..:.|
Mouse   543 AQAARLWPRLQHLNLSSCSQLTEQTLDTIGQ 573

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jetNP_608880.2 leucine-rich repeat 85..110 CDD:275381 6/42 (14%)
AMN1 96..>261 CDD:187754 50/219 (23%)
leucine-rich repeat 111..137 CDD:275381 8/25 (32%)
leucine-rich repeat 138..163 CDD:275381 6/24 (25%)
leucine-rich repeat 164..189 CDD:275381 11/59 (19%)
leucine-rich repeat 190..215 CDD:275381 7/26 (27%)
leucine-rich repeat 216..241 CDD:275381 8/24 (33%)
leucine-rich repeat 242..267 CDD:275381 6/24 (25%)
leucine-rich repeat 268..290 CDD:275381 7/22 (32%)
Lrrc29NP_001355337.1 F-box-like 3..38 CDD:372399
leucine-rich repeat 70..83 CDD:275381
LRR_RI <118..360 CDD:393385 16/73 (22%)
leucine-rich repeat 121..154 CDD:275381
leucine-rich repeat 155..180 CDD:275381
leucine-rich repeat 181..227 CDD:275381
leucine-rich repeat 228..248 CDD:275381
AMN1 240..428 CDD:187754 35/141 (25%)
leucine-rich repeat 254..277 CDD:275381
leucine-rich repeat 280..305 CDD:275381
leucine-rich repeat 306..360 CDD:275381 16/73 (22%)
leucine-rich repeat 331..356 CDD:275381 5/36 (14%)
leucine-rich repeat 361..387 CDD:275381 8/25 (32%)
leucine-rich repeat 388..413 CDD:275381 6/24 (25%)
leucine-rich repeat 414..474 CDD:275381 11/59 (19%)
AMN1 <475..589 CDD:187754 29/102 (28%)
leucine-rich repeat 475..525 CDD:275381 15/52 (29%)
leucine-rich repeat 526..551 CDD:275381 6/24 (25%)
leucine-rich repeat 552..577 CDD:275381 7/22 (32%)
leucine-rich repeat 578..603 CDD:275381
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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