Protein Alignment jet and FBXL13

DIOPT Version :9

• Sequence 1: NP_608880.2
• Gene: jet / 33705
• FlyBaseID: FBgn0031652
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001381423.1
• Gene: FBXL13 / 222235
• HGNCID: 21658
• Length: 825
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 72/289 - (24%)
• Similarity: 127/289 - (43%)
• Gaps: 57/289 - (19%)

  Fly    56 VYLSLKDLFNL--RC-------CSR-TAQRFVEA---------ALE--KRQELHLSGNNTKNIDV 99
            ::|::.|:..|  .|       ||| |:..|..|         ||.  |.:::...||. :..|.
Human   443 MHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEGNK-RVTDA 506

  Fly   100 AFRVLARCCQRLEVLHLACCRWLTDELLLPL----------LAN----------------NKKRL 138
            :|:.:.:....|..:::|.|:.:||..|..|          |||                ...|:
Human   507 SFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANCVRIGDMGLKQFLDGPASMRI 571

  Fly   139 WAVNLNECVNITALSLQPIIVECKELRVLKLSKCQWLTTGAVDALTLHQSKLVEFDISYCGAIGE 203
            ..:||:.||.::..|:..:...|..|..|.|..|:.||...:..: ::...||..|:|......|
Human   572 RELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYI-VNIFSLVSIDLSGTDISNE 635

  Fly   204 RCLIIFFRKLNKLTVLSLANTPSVTDQVLIQIGNYCRE---LEHINVIGCAAISDYGVHALTVHC 265
            ...::...|  ||..||::....:||.   .|..:|:.   |||::|..|:.:||..:.||.::|
Human   636 GLNVLSRHK--KLKELSVSECYRITDD---GIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYC 695

  Fly   266 LRLRTLLIRRCPRVTELSLAPLRQRRLYI 294
            :.|.:|.|..||::|:.::..|..:..|:
Human   696 INLTSLSIAGCPKITDSAMEMLSAKCHYL 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jet	NP_608880.2	leucine-rich repeat	85..110	CDD:275381	4/24 (17%)
		AMN1	96..>261	CDD:187754	46/193 (24%)
		leucine-rich repeat	111..137	CDD:275381	10/51 (20%)
		leucine-rich repeat	138..163	CDD:275381	6/24 (25%)
		leucine-rich repeat	164..189	CDD:275381	6/24 (25%)
		leucine-rich repeat	190..215	CDD:275381	6/24 (25%)
		leucine-rich repeat	216..241	CDD:275381	7/24 (29%)
		leucine-rich repeat	242..267	CDD:275381	10/24 (42%)
		leucine-rich repeat	268..290	CDD:275381	7/21 (33%)
FBXL13	NP_001381423.1	Sfi1	<112..>224	CDD:400658
		F-box-like	245..289	CDD:403981
		leucine-rich repeat	285..312	CDD:275381
		AMN1	312..497	CDD:187754	13/53 (25%)
		leucine-rich repeat	313..336	CDD:275381
		leucine-rich repeat	337..362	CDD:275381
		leucine-rich repeat	363..387	CDD:275381
		leucine-rich repeat	388..406	CDD:275381
		leucine-rich repeat	416..441	CDD:275381
		leucine-rich repeat	442..491	CDD:275381	12/47 (26%)
		leucine-rich repeat	468..490	CDD:275381	5/21 (24%)
		leucine-rich repeat	492..515	CDD:275381	4/23 (17%)
		leucine-rich repeat	518..542	CDD:275381	7/23 (30%)
		AMN1	529..737	CDD:187754	52/202 (26%)
		leucine-rich repeat	543..570	CDD:275381	3/26 (12%)
		leucine-rich repeat	571..596	CDD:275381	6/24 (25%)
		leucine-rich repeat	597..645	CDD:275381	12/50 (24%)
		leucine-rich repeat	646..671	CDD:275381	7/27 (26%)
		leucine-rich repeat	672..697	CDD:275381	10/24 (42%)
		leucine-rich repeat	698..723	CDD:275381	7/24 (29%)
		leucine-rich repeat	724..749	CDD:275381	0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810