DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jet and B0393.3

DIOPT Version :9

Sequence 1:	NP_608880.2	Gene:	jet / 33705	FlyBaseID:	FBgn0031652	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_497980.1	Gene:	B0393.3 / 175630	WormBaseID:	WBGene00007168	Length:	621	Species:	Caenorhabditis elegans

Alignment Length:	284	Identity:	59/284 - (20%)
Similarity:	106/284 - (37%)	Gaps:	71/284 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LFDVC---------WDDVLIPQVAVYLSLKDLFNLRCCSRTAQ----RFVEAALEKRQELHLSGN 92
            ||..|         |...:|..|.....||.|..|.||....:    :.:.....:.:||.:..:
Worm   110 LFRSCSLREYTQWSWRQSVISSVTRCPQLKQLDILICCRHRLRDGDLQVIFKQCNQLEELRMDAS 174

  Fly    93 NTKNIDVAFRVLARCCQRLEVLHLACCRWLTDELLLPLLAN-NKKRLWAVNLNECVNITALSLQP 156
            ....     ...::..|.|..|.|.||:.|..:..:.:.:. .|.:...|:|.:|::      :.
Worm   175 YING-----HCFSKAPQTLRKLELECCQTLNKQGFIGMCSRLFKLQTLHVSLMQCID------EQ 228

  Fly   157 IIVECKELRVLKLSKCQWLTTGAVDALTLHQSKLVEFDISYCGAIGERCLIIFFRKLNKLTVLSL 221
            :|....:::.||.     |:..|.....::|.:|.|                 .|:|:|||.|.|
Worm   229 LIKRIGDMKSLKN-----LSVVADPDQKMNQFRLAE-----------------IRRLSKLTTLCL 271

  Fly   222 ANTPSVTDQVLIQIGNYC-----RELEHINVIGCAAISDYGVHALTVHCLRLRTLLIRRCPRVTE 281
            ....:|||:.|..:.:..     ..:||:::..|..|...|:.       :|:||     |.:..
Worm   272 DGVNNVTDKFLGDLSDLSTSPAGSSIEHLSLSFCKNIGSNGIS-------KLKTL-----PNLKS 324

  Fly   282 LSLAPLRQRRLYIDRPQPDVGLNA 305
            |:|..:.:|.:       ..||.|
Worm   325 LNLDGVSKRDI-------STGLEA 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jet	NP_608880.2	leucine-rich repeat	85..110	CDD:275381	2/24 (8%)
		AMN1	96..>261	CDD:187754	35/170 (21%)
		leucine-rich repeat	111..137	CDD:275381	7/26 (27%)
		leucine-rich repeat	138..163	CDD:275381	4/24 (17%)
		leucine-rich repeat	164..189	CDD:275381	5/24 (21%)
		leucine-rich repeat	190..215	CDD:275381	4/24 (17%)
		leucine-rich repeat	216..241	CDD:275381	8/29 (28%)
		leucine-rich repeat	242..267	CDD:275381	5/24 (21%)
		leucine-rich repeat	268..290	CDD:275381	6/21 (29%)
B0393.3	NP_497980.1	leucine-rich repeat	103..137	CDD:275381	6/26 (23%)
		leucine-rich repeat	138..165	CDD:275381	6/26 (23%)
		leucine-rich repeat	188..213	CDD:275381	6/24 (25%)
		leucine-rich repeat	214..265	CDD:275381	13/78 (17%)
		LRR	232..>389	CDD:227223	33/151 (22%)
		AMN1	<262..408	CDD:187754	25/99 (25%)
		leucine-rich repeat	266..296	CDD:275381	8/29 (28%)
		leucine-rich repeat	297..321	CDD:275381	8/35 (23%)
		leucine-rich repeat	348..373	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900