DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jet and fbxl13

DIOPT Version :9

Sequence 1:	NP_608880.2	Gene:	jet / 33705	FlyBaseID:	FBgn0031652	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_017209779.1	Gene:	fbxl13 / 101883454	ZFINID:	ZDB-GENE-140106-120	Length:	796	Species:	Danio rerio

Alignment Length:	280	Identity:	76/280 - (27%)
Similarity:	121/280 - (43%)	Gaps:	51/280 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SLFDVCWDDVLIP--QVAVYLSLKDLFNLRCCSRTAQRFVEAALEKRQELHLSGNNTKNIDVAFR 102
            :|.|:| ..||:.  ::...:||.:..||   |..|.:.|...::..:.| :.||:... |.:.:
Zfish   461 TLTDIC-VQVLVSRCRMLTVISLLESLNL---SDVAFKAVAEVIDLTKIL-IEGNDVIT-DSSVK 519

  Fly   103 VLARCCQRLEVLHLACCRWLTDELL-----LPLLAN---------------------NKKRLWAV 141
            .|.|.|.:|..|||:||..:||...     |..|.|                     :..:|..:
Zfish   520 ALCRSCLKLSELHLSCCPRVTDACFKTLGNLTKLCNLNISGCFKVTDMGLHYITEGPSAGQLREL 584

  Fly   142 NLNECVNITALSLQPIIVECKELRVLKLSKCQWLTTGAVDALTLHQSKLVEFDISYC-------G 199
            :|:.|:.||.|||:.|..:|..|..|.|..|:.||....:.|. ..|.|:..|||.|       .
Zfish   585 DLSYCLKITDLSLRRISQKCISLTNLALCFCENLTDNGFECLD-KCSSLISLDISGCKIHDKGLS 648

  Fly   200 AIGERCLIIFFRKLNKLTVLSLANTPSVTDQVLIQIGNYCRELEHINVIGCAAISDYGVHALTVH 264
            |:|..         ..|..||.|....:||..:......|:.||.::|..|..:||..:.||:..
Zfish   649 ALGAN---------PSLRKLSAAECVFITDIGIKMFCRLCQRLELLDVCQCVRLSDRAIKALSFF 704

  Fly   265 CLRLRTLLIRRCPRVTELSL 284
            |..:.|:.|..||::|:.::
Zfish   705 CRTIATVRIAGCPKMTDAAV 724

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jet	NP_608880.2	leucine-rich repeat	85..110	CDD:275381	7/24 (29%)
		AMN1	96..>261	CDD:187754	53/197 (27%)
		leucine-rich repeat	111..137	CDD:275381	11/51 (22%)
		leucine-rich repeat	138..163	CDD:275381	10/24 (42%)
		leucine-rich repeat	164..189	CDD:275381	7/24 (29%)
		leucine-rich repeat	190..215	CDD:275381	7/31 (23%)
		leucine-rich repeat	216..241	CDD:275381	7/24 (29%)
		leucine-rich repeat	242..267	CDD:275381	9/24 (38%)
		leucine-rich repeat	268..290	CDD:275381	5/17 (29%)
fbxl13	XP_017209779.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900