DRSC/TRiP Functional Genomics Resources

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Protein Alignment jet and Fbxl14

DIOPT Version :9

Sequence 1:NP_608880.2 Gene:jet / 33705 FlyBaseID:FBgn0031652 Length:319 Species:Drosophila melanogaster
Sequence 2:NP_598701.2 Gene:Fbxl14 / 101358 MGIID:2141676 Length:400 Species:Mus musculus


Alignment Length:251 Identity:63/251 - (25%)
Similarity:110/251 - (43%) Gaps:12/251 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 DVLIPQVAVYLSLKDLFNLRCCS---RTAQRFVEAALEKRQEL------HLSGNNTKNIDVAFRV 103
            |..:.::|.||...::..|..||   .|....:...|::.:.|      |||.....::....|.
Mouse   132 DSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRS 196

  Fly   104 LARCCQRLEVLHLACCRWLTDELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKELRVLK 168
            .|..|..||.|.|..|:.||| |.|..::.....|..:||:.|..|:...|.. :.....||.|.
Mouse   197 AAEGCLGLEQLTLQDCQKLTD-LSLKHISRGLTGLRLLNLSFCGGISDAGLLH-LSHMGSLRSLN 259

  Fly   169 LSKCQWLTTGAVDALTLHQSKLVEFDISYCGAIGERCLIIFFRKLNKLTVLSLANTPSVTDQVLI 233
            |..|..::...:..|.:...:|...|:|:|..:|::.|....:.|:.|..|||.:. .::|..:.
Mouse   260 LRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSC-HISDDGIN 323

  Fly   234 QIGNYCRELEHINVIGCAAISDYGVHALTVHCLRLRTLLIRRCPRVTELSLAPLRQ 289
            ::......|..:|:..|..|:|.|:..:..|..:|..:.:..|.|:|:..|..:.|
Mouse   324 RMVRQMHGLRTLNIGQCVRITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQ 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
jetNP_608880.2 leucine-rich repeat 85..110 CDD:275381 7/30 (23%)
AMN1 96..>261 CDD:187754 43/164 (26%)
leucine-rich repeat 111..137 CDD:275381 10/25 (40%)
leucine-rich repeat 138..163 CDD:275381 6/24 (25%)
leucine-rich repeat 164..189 CDD:275381 6/24 (25%)
leucine-rich repeat 190..215 CDD:275381 7/24 (29%)
leucine-rich repeat 216..241 CDD:275381 5/24 (21%)
leucine-rich repeat 242..267 CDD:275381 7/24 (29%)
leucine-rich repeat 268..290 CDD:275381 6/22 (27%)
Fbxl14NP_598701.2 Required for down-regulation of SNAI1. /evidence=ECO:0000250 2..48
F-box-like 5..46 CDD:403981
AMN1 90..296 CDD:187754 43/165 (26%)
leucine-rich repeat 92..118 CDD:275381
leucine-rich repeat 119..142 CDD:275381 2/9 (22%)
LRR 1 144..163 4/18 (22%)
leucine-rich repeat 145..170 CDD:275381 5/24 (21%)
LRR 2 170..191 4/20 (20%)
leucine-rich repeat 171..203 CDD:275381 7/31 (23%)
LRR 3 203..225 10/22 (45%)
leucine-rich repeat 204..229 CDD:275381 10/25 (40%)
AMN1 228..395 CDD:187754 37/154 (24%)
LRR 4 229..250 6/21 (29%)
leucine-rich repeat 230..254 CDD:275381 6/24 (25%)
LRR 5 254..275 5/20 (25%)
leucine-rich repeat 255..280 CDD:275381 6/24 (25%)
leucine-rich repeat 281..306 CDD:275381 7/24 (29%)
leucine-rich repeat 307..331 CDD:275381 5/24 (21%)
leucine-rich repeat 332..357 CDD:275381 7/24 (29%)
leucine-rich repeat 358..382 CDD:275381 6/22 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1947
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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