DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jet and Fbxl13

DIOPT Version :9

Sequence 1:	NP_608880.2	Gene:	jet / 33705	FlyBaseID:	FBgn0031652	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_038962809.1	Gene:	Fbxl13 / 100125363	RGDID:	1642425	Length:	823	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	65/243 - (26%)
Similarity:	107/243 - (44%)	Gaps:	44/243 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 QELHLSGNNTKNI-DVAFRVLARCCQRLEVLHLACCRWLTDELLLPLLANNKKRLWAVNLNECVN 148
            :::...||  |.| |..|:.:.|....:..:::..|:.|||..|..|  :..|:|..:||..||.
  Rat   489 KKIRFEGN--KRITDACFKSVDRNYPGISHIYMVDCKGLTDSSLKSL--SVLKQLTVLNLTNCVR 549

  Fly   149 ITALSLQ-----PIIVE-----------------------CKELRVLKLSKCQWLTTGAVDALTL 185
            |..:.|:     |..|:                       |..|..|.|..|:.||..|::.:..
  Rat   550 IGDIGLRQFFDGPASVKLRELNLANCSLLGDTSVIRLSERCPNLHYLNLRNCEHLTDLAIEYIAS 614

  Fly   186 HQSKLVEFDISYCGA-IGERCLIIFFRKLNKLTVLSLANTPSVTDQVLIQIGNYCR---ELEHIN 246
            ..| |:..|:|  |. |....|.|..|. .||..:||:...::||   ..|..:|:   .|||::
  Rat   615 MLS-LISIDLS--GTLISNEGLAILSRH-RKLREVSLSECVNITD---FGIRAFCKTSLALEHLD 672

  Fly   247 VIGCAAISDYGVHALTVHCLRLRTLLIRRCPRVTELSLAPLRQRRLYI 294
            |..||.::|..:..:.:.|.|:.:|.|..||::|:..:..|..|..|:
  Rat   673 VSYCAQLTDDIIKTIAIFCTRITSLHIAGCPKITDGGMEILSARCHYL 720

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jet	NP_608880.2	leucine-rich repeat	85..110	CDD:275381	7/25 (28%)
		AMN1	96..>261	CDD:187754	52/197 (26%)
		leucine-rich repeat	111..137	CDD:275381	6/25 (24%)
		leucine-rich repeat	138..163	CDD:275381	10/52 (19%)
		leucine-rich repeat	164..189	CDD:275381	7/24 (29%)
		leucine-rich repeat	190..215	CDD:275381	8/25 (32%)
		leucine-rich repeat	216..241	CDD:275381	7/27 (26%)
		leucine-rich repeat	242..267	CDD:275381	8/24 (33%)
		leucine-rich repeat	268..290	CDD:275381	6/21 (29%)
Fbxl13	XP_038962809.1	Sfi1	<134..>214	CDD:400658
		F-box-like	242..286	CDD:403981
		leucine-rich repeat	257..270	CDD:275381
		leucine-rich repeat	282..308	CDD:275381
		AMN1	308..477	CDD:187754
		leucine-rich repeat	309..332	CDD:275381
		leucine-rich repeat	333..358	CDD:275381
		leucine-rich repeat	359..383	CDD:275381
		leucine-rich repeat	384..402	CDD:275381
		leucine-rich repeat	412..437	CDD:275381
		leucine-rich repeat	438..463	CDD:275381
		leucine-rich repeat	464..486	CDD:275381
		leucine-rich repeat	488..513	CDD:275381	7/25 (28%)
		leucine-rich repeat	514..534	CDD:275381	6/21 (29%)
		AMN1	525..733	CDD:187754	57/205 (28%)
		leucine-rich repeat	539..563	CDD:275381	7/23 (30%)
		leucine-rich repeat	567..592	CDD:275381	1/24 (4%)
		leucine-rich repeat	593..617	CDD:275381	7/23 (30%)
		leucine-rich repeat	618..641	CDD:275381	8/25 (32%)
		leucine-rich repeat	642..667	CDD:275381	7/27 (26%)
		leucine-rich repeat	668..693	CDD:275381	8/24 (33%)
		leucine-rich repeat	694..719	CDD:275381	7/24 (29%)
		leucine-rich repeat	720..745	CDD:275381	0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1947
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900