Protein Alignment betaggt-I and RABGGTB

DIOPT Version :10

• Sequence 1: NP_525100.2
• Gene: betaggt-I / 33704
• FlyBaseID: FBgn0015000
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_004573.2
• Gene: RABGGTB / 5876
• HGNCID: 9796
• Length: 331
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 103/344 - (29%)
• Similarity: 161/344 - (46%)
• Gaps: 59/344 - (17%)

  Fly     3 DRTDTEPVLLSKHAKNLLRFLNLLPARMASH------------DNTRSTIVFFAVCGLDVLNSLH 55
            |..||  :||.|||..:           ||:            :..|.:.:::.:..:|::..||
Human    13 DAPDT--LLLEKHADYI-----------ASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLH 64

  Fly    56 LVPPQLRQDIIDWIYGGLVVPRDNEKNCGGFMGCRAMVPKTEDAEILECMRNYQWGHLAMTYTSL 120
            .:.   |::|:.:|       :..:..|||........|                 ||..|.:::
Human    65 RMN---REEILAFI-------KSCQHECGGISASIGHDP-----------------HLLYTLSAV 102

  Fly   121 AVLVTLGDDLSRLDRKSIVDGVAAVQKPEGSFSACIDGSEDDMRFVYCAATICYMLDYWGDVNKE 185
            .:| ||.|.::.:|...:|:.|..:||.:|||:..|.| |.|.||.:||.....:|.....:|.|
Human   103 QIL-TLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWG-EIDTRFSFCAVATLALLGKLDAINVE 165

  Fly   186 TMFQFITRSLRYDYGFSQELEGEAHGGTTFCALAALHLSGQLHRLDATTVERMKRWLIFRQM--D 248
            ...:|:...:.:|.||......|:|.|..:|....|.::.|||::::   :.:..||..||:  .
Human   166 KAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNS---DLLGWWLCERQLPSG 227

  Fly   249 GFQGRPNKPVDTCYSFWIGASLCILDGFELTDYARNREFILSTQDKLIGGFAKWPQATPDPFHTY 313
            |..|||.|..|.|||:|:.|||.|:......|..:.|.|||:.||:..||||..|....|||||.
Human   228 GLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTL 292

  Fly   314 LGLCGLAFTGEPGLSPVNP 332
            .|:.||:..||..:.||||
Human   293 FGIAGLSLLGEEQIKPVNP 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaggt-I	NP_525100.2	GGTase-I	14..321	CDD:239225	92/320 (29%)
RABGGTB	NP_004573.2	GGTase-II	18..301	CDD:239224	94/325 (29%)
		PFTB 1	20..61		8/51 (16%)
		PFTB 2	68..109		13/65 (20%)
		PFTB 3	116..157		15/41 (37%)
		PFTB 4	164..205		10/40 (25%)
		PFTB 5	212..253		18/43 (42%)
		PFTB 6	260..302		19/41 (46%)