Protein Alignment betaggt-I and FNTB

DIOPT Version :9

• Sequence 1: NP_525100.2
• Gene: betaggt-I / 33704
• FlyBaseID: FBgn0015000
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_002019.1
• Gene: FNTB / 2342
• HGNCID: 3785
• Length: 437
• Species: Homo sapiens
• Alignment Length: 357
• Identity: 95/357 - (26%)
• Similarity: 152/357 - (42%)
• Gaps: 64/357 - (17%)

  Fly    14 KHAKNLLRFLNLLPARMASHDNTRSTIVFFAVCGLDVLNSLHLVPPQLRQDIIDWIYGGLVVPRD 78
            ||...|.|.|..|.......|.:|..:.::      :|:||.|:...:.|.:...:...|.:.:.
Human    77 KHFHYLKRGLRQLTDAYECLDASRPWLCYW------ILHSLELLDEPIPQIVATDVCQFLELCQS 135

  Fly    79 NEKNCGGFMGCRAMVPKTEDAEILECMRNYQWGHLAMTYTSLAVLVTLGDD--LSRLDRKSIVDG 141
            .|...||..|                    |:.|||.||.::..|..:|.:  ...::|:.::..
Human   136 PEGGFGGGPG--------------------QYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQY 180

  Fly   142 VAAVQKPEGSFSACIDGSEDDMRFVYCAATICYMLDYWGDVNKETMFQFITRSLRYDYGFSQELE 206
            :.::::|:|||...: |.|.|:|..||||::..:.:.......|...::|.|...::.|......
Human   181 LYSLKQPDGSFLMHV-GGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPG 244

  Fly   207 GEAHGGTTFCALAALHLSGQLHRLDATTVERMKRWLIFRQM---DGFQGRPNKPVDTCYSFWIGA 268
            .|||||.|||.||||.:   |.|..:..::.:.:|:..|||   .|||||.||.||.|||||...
Human   245 MEAHGGYTFCGLAALVI---LKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAG 306

  Fly   269 SLCIL---------DGFELTDYARN----REFILSTQDKLIGGFAKWPQATPDPFHTYLGLCGLA 320
            .|.:|         ....::.:..:    :|:||.......||....|..:.|.:||...|.||:
Human   307 LLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLS 371

  Fly   321 FT--------------GEP--GLSPVNPSLNM 336
            ..              |.|  .|.|.:|..|:
Human   372 IAQHFGSGAMLHDVVLGVPENALQPTHPVYNI 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaggt-I	NP_525100.2	CAL1	10..336	CDD:227362	94/355 (26%)
		GGTase-I	14..321	CDD:239225	89/324 (27%)
FNTB	NP_002019.1	FTase	75..373	CDD:239223	89/325 (27%)
		PFTB 1	123..164		12/60 (20%)
		PFTB 2	174..215		13/41 (32%)
		PFTB 3	222..263		16/43 (37%)
		Farnesyl diphosphate binding. /evidence=ECO:0000269|PubMed:11687658, ECO:0000269|PubMed:12036349, ECO:0000269|PubMed:12825937, ECO:0000269|PubMed:15451670, ECO:0000269|PubMed:16893176	248..251		2/2 (100%)
		PFTB 4	270..312		19/41 (46%)
		Farnesyl diphosphate binding. /evidence=ECO:0000269|PubMed:11687658, ECO:0000269|PubMed:12036349, ECO:0000269|PubMed:12825937, ECO:0000269|PubMed:15451670, ECO:0000269|PubMed:16893176	291..294		1/2 (50%)
		Farnesyl diphosphate binding. /evidence=ECO:0000269|PubMed:11687658, ECO:0000269|PubMed:12036349, ECO:0000269|PubMed:12825937, ECO:0000269|PubMed:15451670, ECO:0000269|PubMed:16893176	300..303		2/2 (100%)
		PFTB 5	332..374		12/41 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1042804at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820