DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment betaggt-I and Fntb

DIOPT Version :9

Sequence 1:	NP_525100.2	Gene:	betaggt-I / 33704	FlyBaseID:	FBgn0015000	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_666039.1	Gene:	Fntb / 110606	MGIID:	1861305	Length:	437	Species:	Mus musculus

Alignment Length:	365	Identity:	94/365 - (25%)
Similarity:	152/365 - (41%)	Gaps:	80/365 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 KHAKNLLRFLNLLPARMASHDNTRSTIVFFAVCGLDVLNSLHL----VPPQLRQDIIDWIYGGLV 74
            ||...|.|.|..|.......|.:|..:.::      :|:||.|    :|..:..|:..::
Mouse    77 KHFHYLKRGLRQLTDAYECLDASRPWLCYW------ILHSLELLDEPIPQIVATDVCQFL----- 130

  Fly    75 VPRDNEKNC----GGFMGCRAMVPKTEDAEILECMRNYQWGHLAMTYTSLAVLVTLGDD--LSRL 133
                  :.|    |||.|.....|                 |||.||.::..|..:|.:  .:.:
Mouse   131 ------ELCQSPDGGFGGGPGQYP-----------------HLAPTYAAVNALCIIGTEEAYNVI 172

  Fly   134 DRKSIVDGVAAVQKPEGSFSACIDGSEDDMRFVYCAATICYMLDYWGDVNKETMFQFITRSLRYD 198
            :|:.::..:.::::|:|||...: |.|.|:|..||||::..:.:.......|...::|.|...::
Mouse   173 NREKLLQYLYSLKQPDGSFLMHV-GGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWE 236

  Fly   199 YGFSQELEGEAHGGTTFCALAALHLSGQLHRLDATTVERMKRWLIFRQM---DGFQGRPNKPVDT 260
            .|.......|||||.|||.||||.:   |.:..:..::.:.:|:..|||   .|||||.||.||.
Mouse   237 GGIGGVPGMEAHGGYTFCGLAALVI---LKKERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDG 298

  Fly   261 CYSFWIGASLCIL---------DGFELTDYARN----REFILSTQDKLIGGFAKWPQATPDPFHT 312
            |||||....|.:|         ....::.:..:    :|:||.......||....|..:.|.:||
Mouse   299 CYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHT 363

  Fly   313 YLGLCGLAFTGEPG----------------LSPVNPSLNM 336
            ...|.||:.....|                |.|.:|..|:
Mouse   364 CYCLSGLSIAQHFGSGAMLHDMVMGVPENVLQPTHPVYNI 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaggt-I	NP_525100.2	CAL1	10..336	CDD:227362	93/363 (26%)
betaggt-I	NP_525100.2	GGTase-I	14..321	CDD:239225	89/332 (27%)
Fntb	NP_666039.1	PLN02710	42..419	CDD:215380	94/365 (26%)
		FTase	75..373	CDD:239223	89/333 (27%)
		PFTB 1	123..164		13/68 (19%)
		PFTB 2	174..215		13/41 (32%)
		PFTB 3	222..263		16/43 (37%)
		Farnesyl diphosphate binding. /evidence=ECO:0000250\|UniProtKB:P49356	248..251		2/2 (100%)
		PFTB 4	270..312		19/41 (46%)
		Farnesyl diphosphate binding. /evidence=ECO:0000250\|UniProtKB:P49356	291..294		1/2 (50%)
		Farnesyl diphosphate binding. /evidence=ECO:0000250\|UniProtKB:P49356	300..303		2/2 (100%)
		PFTB 5	332..374		12/41 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1042804at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820