DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL24 and mrpl-24

DIOPT Version :9

Sequence 1:	NP_523476.1	Gene:	mRpL24 / 33703	FlyBaseID:	FBgn0031651	Length:	247	Species:	Drosophila melanogaster
Sequence 2:	NP_491613.1	Gene:	mrpl-24 / 172204	WormBaseID:	WBGene00019076	Length:	278	Species:	Caenorhabditis elegans

Alignment Length:	267	Identity:	102/267 - (38%)
Similarity:	146/267 - (54%)	Gaps:	45/267 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 NLPKEYIERSKKQV----------------YWQTPKEINYLP---RTVERKRFRYTTNRS---WT 58
            ::|..|:||:|:.|                |:..|.:  |:|   |..|.|:.....:||   ::
Worm    22 HMPSAYVERTKRTVPRKVFGDRFGAPDIKMYYVHPDD--YVPSHRRPWEDKQISSHLHRSDKYFS 84

  Fly    59 GQFRQQ--NMPGTVRRKVLVEPIED--WSFFRGDRIEVLVGKDKGKQGIVTQVIPERNWVIVEGL 119
            .|...|  |:     |:...|.:.|  |:||.||.::|:||||||:||:|.....:.:.|||:||
Worm    85 AQLSNQYFNL-----RRPKSERMADTEWTFFPGDLVQVMVGKDKGRQGLVLTTSRDSSDVIVDGL 144

  Fly   120 NWHYRKVGGEKEFP---GI---IIKSEAPLHVT-KDIRLVDPSDLQGTDFEWRFTEEG-EKVRVS 176
               :.|:|.:.|..   |:   :...|.||.|: |.:.||||:|.|..:..|:....| |.:|||
Worm   145 ---HTKLGEDMEGSEKLGVDKTLRWQEQPLSVSKKQVMLVDPNDEQPCEARWQLNGPGDEYIRVS 206

  Fly   177 LRSGRIIPIPETNNQTHDYKTPNAYIERE-KDTPGAVVGEITFQPKLSTFEMDIMEEMGIKEERT 240
            .|||..||||.....|::|..|..|||.| ||||...|.|.|:.||:::||.:||||||||||||
Worm   207 TRSGYEIPIPSQAKVTYEYLQPENYIEVEGKDTPADAVLERTYMPKVASFEQEIMEEMGIKEERT 271

  Fly   241 PVKSYWY 247
            |..::||
Worm   272 PKPTFWY 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL24	NP_523476.1	rplX	86..183	CDD:234566	41/104 (39%)
mrpl-24	NP_491613.1	KOW_RPL26	112..180	CDD:240513	26/70 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160595
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0198
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12241
Inparanoid	1	1.050	138	1.000	Inparanoid score	I3101
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52435
OrthoDB	1	1.010	-	-		D1007373at2759
OrthoFinder	1	1.000	-	-		FOG0004182
OrthoInspector	1	1.000	-	-		oto18225
orthoMCL	1	0.900	-	-		OOG6_101141
Panther	1	1.100	-	-	LDO	PTHR12903
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2757
SonicParanoid	1	1.000	-	-		X5232
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.800