DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sgs1 and LOC799643

DIOPT Version :9

Sequence 1:	NP_523475.3	Gene:	Sgs1 / 33701	FlyBaseID:	FBgn0003372	Length:	1286	Species:	Drosophila melanogaster
Sequence 2:	XP_017211382.2	Gene:	LOC799643 / 799643	-ID:	-	Length:	1044	Species:	Danio rerio

Alignment Length:	948	Identity:	322/948 - (33%)
Similarity:	465/948 - (49%)	Gaps:	122/948 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 TTTPRSTTTTTTRRPTTTTPRCTTT--TSTCAPTTTTPRSTTTTTTSRPTTTTPRCTTTTSTCSP 315
            |..|...|||||  |||.|...|.:  |....|||.|..:|.:..||.          |||:.:.
Zfish    27 TLAPSIVTTTTT--PTTVTTETTASNLTFVIPPTTATSETTPSNLTSE----------TTSSNAT 79

  Fly   316 TRTTPRSTTTTSTSRPTTTTPRCTTTPSTSRPTTTTPRSTTKTSTCAPTTTTPRPTTTPSTSRPT 380
            :.|||.:.|:.:|  |:..|...|.:.:||.   |||.:.|..:|.:..|:..:|:...|..:|:
Zfish    80 SETTPSNVTSETT--PSNVTSETTPSNATSE---TTPSNVTSETTPSNVTSEIKPSNVTSEIKPS 139

  Fly   381 TTTPRSTTTTSTSRPTTTTPRSTTTTTTRRPTT--TTPRSTT--TTSTSRPTTTTPRSTTTTTTS 441
            ..|..:|.:..||.   |||.:.|:.||....|  |||.:.|  ||.::..:.|||.:.|:.||
Zfish   140 NVTSETTPSNVTSE---TTPSNVTSETTPSNVTLETTPSNVTSETTPSNVASETTPSNVTSETT- 200

  Fly   442 RPTTTTPRSTTTTCTCSPTTTTPRSTTTTSTSRPTTTTPRSTTTTSTSGPTTTTPRSTTTTTTSG 506
             |:..|..:|.:..|   :.|||.:.|:.:|....|:....||.||.:.|||.|..:..||.||
Zfish   201 -PSNVTSETTPSNVT---SETTPSNMTSETTPSNVTSVNTPTTATSATIPTTATSATILTTATS- 260

  Fly   507 PTTTTPRSTTTTCTCSPTTTTPRSTTTPSTSRPTTTTPRSTTTTCTCSPTT-TTPRSTTTTSTSR 570
              .|||.:.|:..|.|..|    |.||||.....||....|:.|...:.|: |||.:.|:.:|
Zfish   261 --ETTPSNATSETTPSKVT----SATTPSNMTLETTHLNVTSETINSNVTSETTPLNVTSVNT-- 317

  Fly   571 PTTTTPRSTTTTTTSR--PTTTTPRSTTTTSTSGPTTTTPRSTTTTSTSGPTTTTPRSTTTTSTS 633
            |||.|..:..||.||.  ||..|.::|....|| .||....:..||.::|.:.|.|  ||.|||:
Zfish   318 PTTATLATIPTTATSATIPTIATSKTTPLNVTS-VTTAITVTLETTPSNGTSVTKP--TTATSTA 379

  Fly   634 GPTTTTPRSTTTTSTSGPTTTTPRSTTTTSTSGPTTTTPRSTTTTSTSGPTTTTPRSTTTTSTSG 698
            .||..|..:|.:|:||..|:||....|||:||..|:||..|.||     |:|.|..:|:||:.|.
Zfish   380 SPTAATLETTPSTATSATTSTTAILATTTATSATTSTTAISATT-----PSTATSATTSTTAISA 439

  Fly   699 PTTTTPRSTTTTSTSGPTTTTPRSTTTTSTSGPTTTTPRSTTTTSTSGPTTTTPRSTTTTSTSGP 763
            .|.:|..|.||::.:...||   .:|..|.:.|:|:|..:|:||:.|..|.:...|:||.||: .
Zfish   440 TTPSTVPSATTSAIAILATT---HSTEISATTPSTSTSATTSTTAISATTPSIDTSSTTPSTA-T 500

  Fly   764 TTTTPRSTTTTSTSGPTTTTPRSTTTTSTSGPTTTTPRSTTTTSTSGPTTTTPRSTTTTSTSGPT 828
            :.|||  :|.||.:.|:|.|..:|.:|:||..|.:|..|.||.||: .:.|||  :|.||.:.|.
Zfish   501 SATTP--STATSATTPSTATSATTPSTATSATTPSTATSATTPSTA-TSATTP--STATSATAPL 560

  Fly   829 TTTPRSTTTTSTSGPTTTTPRSTTTTSTSGPTTTTPRSTTTTSTSGPTTTTPRSTTTTSTSGPTT 893
            |.|..:|.:::||..|:||..|.||.|.. .:.|||  :|.||.:.|.|.|   :.||.:|..:.
Zfish   561 TVTSATTHSSATSATTSTTETSATTPSFE-TSATTP--STATSATAPLTVT---SATTHSSATSA 619

  Fly   894 TTPRSTTTTSTSGPTTTTPRSTTTTSTSCPTTTTPRS----TTTTCTSGPTTTTPRSTTTTCTSC 954
            |||...|:.:||  ||.|..:|.:.:||..|..|..|    :|.|..:.|:|.|..:|.:|.|..
Zfish   620 TTPSFVTSATTS--TTETSANTPSFATSVTTPLTESSAITHSTMTLATTPSTVTRATTPSTVTRT 682

  Fly   955 PTTTTPRSTTTTCTSCPTTTTPRSTTTTCTSGPTTTTPRSTTK---TSTCAPTTTTPRSTTTTST 1016
            |   ||.:.||..|  |:|.|..:|.:|.|   |.|||.:.||   |||...|.|||.|||.:::
Zfish   683 P---TPSNATTVIT--PSTVTRATTPSTAT---TVTTPSTVTKATTTSTATTTVTTPSSTTRSNS 739

  Fly  1017 SRPTTTTPRSTTTTTTSRPTTTTPRSTTTP--------STSRPTTTTPRSTTTTSTSRPTTTTPR 1073
            :   :|...|.:::|..:.|..|.::||||        |.|...|.|.::..|...:..|.....
Zfish   740 A---STVTGSASSSTGGKSTAGTYQTTTTPPPANLGVISLSFKLTDTFQAVYTDLNNAVTKAYVE 801

  Fly  1074 ----------------------STTKTSTCAPTTTTPRSTTTTTTSRPTTTTPRSTTTTTTS--- 1113
                                  :.....:.|..:|....||::||  |..|..::|.....:
Zfish   802 NIKSQFYPVYKKRYPNYFGMIINKLSAGSVAADSTLQFDTTSSTT--PNATDAKNTLIQAINSGG 864

  Fly  1114 -RPTTTTPRSTTTPCTSRPTTTTPRSTTTTTTSRPTTT 1150
             ..|......|....:|..|:|...||..|.|:...||
Zfish   865 INLTIDNTSITAVQVSSNGTSTAASSTAITQTTTVATT 902

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sgs1	NP_523475.3	None
LOC799643	XP_017211382.2	COG3942	51..>344	CDD:332523	108/324 (33%)
		DUF4573	90..>225	CDD:317546	46/147 (31%)
		SEA	775..886	CDD:321958	19/112 (17%)
		SEA	908..1003	CDD:307516
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000