Protein Alignment hoe2 and Oca2

DIOPT Version :9

• Sequence 1: NP_608878.1
• Gene: hoe2 / 33700
• FlyBaseID: FBgn0031649
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_068679.1
• Gene: Oca2 / 18431
• MGIID: 97454
• Length: 833
• Species: Mus musculus
• Alignment Length: 711
• Identity: 258/711 - (36%)
• Similarity: 393/711 - (55%)
• Gaps: 86/711 - (12%)

  Fly   172 W-KRGGLLVFWILSAVVLISVGEKHLLEKTIDVPMGEEGKFFKLLQ-KPTGDFRLKIHG-AFREL 233
            | |..||.||.:|.: :|.|:             ..::|||::||. .|..::.:.:.| |...:
Mouse   173 WIKITGLFVFVVLCS-ILFSL-------------YPDQGKFWQLLAVSPLENYSVNLSGHADSMI 223

  Fly   234 STLD--------APE------------NETLSFGFLTVQPQVSTYIGENHSQVFQDILPAWRLPL 278
            ..||        .|.            .:|.:.|....:||..||              .|.: |
Mouse   224 LQLDLAGALMAGGPSGSGKEEHVVVVVTQTDAAGNRRRRPQQLTY--------------NWTV-L 273

  Fly   279 LSEEELMLRAPAVTTNRTYQMT--QELDEMLAGKNSEFRLHIYSDVEVDLAIVLNYNPLIVNART 341
            |:.     |:..|..:||:::.  :.:...:.....:.||       |.|.:...:....|.|:.
Mouse   274 LNP-----RSEHVVVSRTFEIVSREAVSISIQASLQQTRL-------VPLLLAHQFLGASVEAQV 326

  Fly   342 GS---ILAGVILLIFYALLVWELFERTFVAMICSILSVTTLACFNDRPNMDEIIQWMDMELLTLL 403
            .|   |||||     |.|:::|:..||..||:.::.::..||...|||::..:::|:|.|.|.||
Mouse   327 ASAVAILAGV-----YTLIIFEIVHRTLAAMLGALAALAALAVVGDRPSLTHVVEWIDFETLALL 386

  Fly   404 FCMMLLILILTETGVFDYLAVFCFEISGGKIWPMIYSLCLVTCLVSSVLDNMTTVLLLTPVAIRL 468
            |.||:|:.:.:|||.|||.||..:::|.|::|.||:.|||:..::|:.|||:||:||.|||.|||
Mouse   387 FGMMILVAVFSETGFFDYCAVKAYQLSRGRVWAMIFMLCLMAAILSAFLDNVTTMLLFTPVTIRL 451

  Fly   469 CEVMQLDPLPVVMGIIVHANIGGALTPIGDPISIIVSTNHFIVDNDVTFPTFVAHTFPGVILAVI 533
            |||:.|||..|::..::..|||||.|.||||.::|:.:|..:....:.|..|.||.|.|:.|.::
Mouse   452 CEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLDFAGFTAHMFLGICLVLL 516

  Fly   534 QSCVYLRLFYHNIDALRLNEPKEMSELRREMKVWQRALNAVASCSKDAQLVRGTLQAKIKQLKRT 598
            .|...|||.|.| ..|...||.|:.||:.|:.||:.....::..|::...|||.|..|:..|:..
Mouse   517 VSFPLLRLLYWN-KKLYNKEPSEIVELKHEIHVWRLTAQRISPASREETAVRGLLLEKVLALEHL 580

  Fly   599 L--------RRLQKGVGSTEVYTNTLDELKQKYPIKNKTLLLQSAGALLFVIVCFFIQSVPHWRT 655
            |        |::.:...:.|  || :.||::|:.|.:::||::....|.|||..||:.|......
Mouse   581 LAQRLHTFHRQISQEDKNWE--TN-IQELQRKHRISDRSLLVKCLTVLGFVISMFFLNSFVPGIH 642

  Fly   656 LPLGWVALLGVILLLIILNRDDMEHLMHRIEWTTLLFFAAMFVMMECVERLGIFACISELTEHVI 720
            |.|||:|:||.|.|||:.:..|.|.::||:||.|||||||:||:||.:..|.:...:.|.|..:|
Mouse   643 LDLGWIAILGAIWLLILADIHDFEIILHRVEWATLLFFAALFVLMEALTHLHLVEYVGEQTALLI 707

  Fly   721 LSVGKSHRLAMAIFMILWMSALASSILDSIPVAAIMVKLVTSLVAKPSLGLPLQPLVWALTLGAS 785
            ..|.:..|.|.||.:|:|:||||||::|:||..|.|:.::.:|...|.:.||..||::||.|||.
Mouse   708 KMVPEDQRFAAAIVLIVWVSALASSLIDNIPFTATMIPVLLNLSQDPEISLPALPLMYALALGAC 772

  Fly   786 MGGNGTLYGASANVIAAGIAEQHGYKLSFTRYLRTVFPMMLGQITLMTVYLLVAHVVFEWH 846
            :||||||.|||.||:.|||||:|||..||..:.|..||:||...|:...|||:||:|..|:
Mouse   773 LGGNGTLIGASTNVVCAGIAEKHGYGFSFMEFFRLGFPVMLMSCTIGMCYLLIAHIVVGWN 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hoe2	NP_608878.1	ArsB	343..837	CDD:223983	213/504 (42%)
		P_permease	350..837	CDD:238536	207/494 (42%)
Oca2	NP_068679.1	P_permease	333..824	CDD:238536	211/499 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836902
Domainoid	1	1.000	426	1.000	Domainoid score	I610
eggNOG	1	0.900	-	-		E1_COG1055
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	522	1.000	Inparanoid score	I1248
Isobase	1	0.950	-	0	Normalized mean entropy	S7077
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001813
OrthoInspector	1	1.000	-	-		otm43375
orthoMCL	1	0.900	-	-		OOG6_101594
Panther	1	1.100	-	-	O	PTHR43568
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2794
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.700