DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3036 and SOA1

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_012100.1	Gene:	SOA1 / 854640	SGDID:	S000001428	Length:	542	Species:	Saccharomyces cerevisiae

Alignment Length:	546	Identity:	106/546 - (19%)
Similarity:	190/546 - (34%)	Gaps:	181/546 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 LNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTASPDGVDVYEERFPWDSYQTNFVLGC 96
            |...|.|.:..|.:|::|.|:..||:...:              ||:......::..||.:::
Yeast    79 LKIFLWVFIMFAFLDLIRKNIARAVSDNFI--------------VDLKMNTNDYNLGQTVYLV-- 127

  Fly    97 FFWGYILTELPGGRLAELIGGRRVFG-HSMLWASLLTLITPLAAHINYVVLIVVRVVLGFMLGAS 160
               .::.:||||..|::..|..||.. ..:||:  :..||. |...|....|..|.:||.:.|.
Yeast   128 ---IFLASELPGNLLSKRFGPERVIPVQIVLWS--VICITQ-AGLKNRGQFIATRCLLGMVQGG- 185

  Fly   161 WPAIHPVAAVWIPPMERSKFMSNMMASS---LGAAIT------------MPICGYLI-------- 202
                      :||        .|::..|   .||.:|            ..|.|.|:
Yeast   186 ----------FIP--------DNILYLSYYYTGAELTFRLSFFWCAIPLFQILGSLLASGIIEMR 232

  Fly   203 ---SVAGWASVFYLTGAVGLLWSLAWFTFVYETP------ATHPRISA----EERREIEEAIGTT 254
               ::|||..:|.:.|.:.|...:|.|..:...|      |.|...|.    ||:..:...:...
Yeast   233 GIHNLAGWQYLFIIEGFLSLSVGVASFYLMRRGPTQTGESAFHKGKSLFTEYEEKIMVNRILRDD 297

  Fly   255 TSKKRPSHVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILH----FD-----IKQN 310
            .||...|                               |:.|....:||:    ||     |:..
Yeast   298 PSKGDMS-------------------------------NRQPVTFKEILYTLTEFDLWPLFIQGI 331

  Fly   311 GLFSSLPYLGKYVMAVA-----SSYLADYLRKKG--------TLSTTATRKL-------FTTFAL 355
            ..|.||..:|.|:..:.     |::|::.|...|        .|:...:|||       ......
Yeast   332 TAFISLQTVGSYLSLILKSLNYSTFLSNILAIPGQALLLINLPLAALLSRKLKEKSLCVGIANVW 396

  Fly   356 VIPGLLMIVQVFLGYDAT-WSVTIFSLAL----FAHGAVTAGYLGNGLDIAPNFGGTIFGLA--N 413
            |:|.::.:|.  |..|.. |...|....:    :.| ::.||::.   :|:.:......|.|  |
Yeast   397 VLPFIVSLVA--LPTDTNPWIKYILLTGILGLPYTH-SILAGWVS---EISNSVRSRTVGTALYN 455

  Fly   414 TLSSFGGFLSTSMVGALTYKDQ-------------SFHSWQIVFWILAATYISAAVVFAILGSGE 465
            ..:..|..::::|     |::.             .|..:.|.        ::.|..|..:...:
Yeast   456 MSAQVGAIIASNM-----YRNDDKPYYTRGNKILLGFTCFNIC--------MAVATKFYYISRNK 507

  Fly   466 L--QPWNN--PPERVRISDVTQEEGV 487
            .  :.||:  ..|::...|.|:::|:
Yeast   508 YKDRKWNSMTKEEQINYLDTTKDKGM 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	103/534 (19%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	89/463 (19%)
SOA1	NP_012100.1	MFS_FEN2_like	76..496	CDD:340885	98/507 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I1824
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050