DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and TNA1

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_011776.1	Gene:	TNA1 / 853175	SGDID:	S000003492	Length:	534	Species:	Saccharomyces cerevisiae

Alignment Length:	545	Identity:	113/545 - (20%)
Similarity:	188/545 - (34%)	Gaps:	161/545 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EKGGLQRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANS 69
            ||..|:::..:|     :.|:.||.|:.|                      ::.:.:||:..|..
Yeast    81 EKRVLRKMDIYL-----IPLMGMLYFLSN----------------------LDKSNIGNAEVAGL 118

  Fly    70 TASPDGVDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLI 134
            :.....|..          |.|..:..||..|:|.:..|..|.:::|...:....:.....::|.
Yeast   119 SKDIHLVGT----------QYNTCVTVFFATYVLFDPIGTNLLKIMGPPLMMSICLTCFGAISLG 173

  Fly   135 TPLAAHINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSK--------FMSNMMASSLGA 191
            |....  ||..|||||::||...|..:|||:...:|.   ..|.:        |.:..::||.|.
Yeast   174 TAWVK--NYAQLIVVRLLLGAFEGMIYPAINMYLSVC---YRREQYALRFAFVFSAACLSSSFGG 233

  Fly   192 AITMPICGYLISVAGWASVFYLTG----------AVGLLWSL--AWFTFVYETPATHPRISAEER 244
            .|.........|:..|..::.:.|          |.||..:|  :||            .:.||:
Yeast   234 LIAYGCSKISGSLKDWQYIYIVEGCISLGFVPFYAFGLSKNLEDSWF------------FNKEEK 286

  Fly   245 REIEEAIGTTTSKKRPSHVPWGQL---LCSPAVWAIIIC--------HGLAVF--------GFFT 290
            ..|.|...|..:........|.|:   :.....||..:.        .||.||        ||..
Yeast   287 EYISERYKTMNTFDPDEKFEWFQVWQAVKDVKTWASAVALFGIDLTTFGLTVFLPIIITSMGFTN 351

  Fly   291 VVNQLPT----FMSKILHFDIKQNGLFSSLPYLGKYVMAVASSYLADYLRKKGTLSTTATRKLFT 351
            |..||.|    |::.|:.|                 :.||.|..:.  ||....|....|..:
Yeast   352 VRAQLMTVPIYFLTAIVFF-----------------ICAVWSDRIK--LRSPFILGACLTTSI-- 395

  Fly   352 TFALVIPGLLMIVQVFLGYDATWSVTIFSLALFAHGAVT----AGYLGNGLDIAPNFGGTIFGLA 412
            ..|:|:...:..|:.|       .|.|..:.::.:.|..    :|..||....|...|..:|
Yeast   396 GIAIVLGSQVHGVRYF-------GVYILCMGIYVNAACNCLWLSGNTGNYFKRATALGINLF--- 450

  Fly   413 NTLSSFGGFLSTSMVGALTYKDQSFH----SWQIVFWILAATYISAAVVF----------AILGS 463
              ..|..|.:|..:..|   ||:..:    |..:.|.:. :.:::...:|          ||:..
Yeast   451 --FGSGSGLVSGQIFVA---KDKPRYIKGLSISLAFQVF-SIFMTVVQIFLYKRENDKKKAIIDR 509

  Fly   464 ----GELQPWNNPPERVRISDVTQE 484
                ||..|::.     |:||...|
Yeast   510 CNELGEPIPYDE-----RLSDKNPE 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	105/522 (20%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	92/438 (21%)
TNA1	NP_011776.1	MFS_FEN2_like	87..490	CDD:340885	100/493 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I2826
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I1824
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050