DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and FEN2

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_009957.1	Gene:	FEN2 / 850394	SGDID:	S000000623	Length:	512	Species:	Saccharomyces cerevisiae

Alignment Length:	507	Identity:	89/507 - (17%)
Similarity:	164/507 - (32%)	Gaps:	158/507 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTASPDGVDVYEERFPWDSYQTNF 92
            |.:.:||..||..|.|.:..::.::      .:|||....::|.
Yeast    43 LQYWINYVDRVGFTNAYISGMKEDL------KMVGNDLTVSNTV--------------------- 80

  Fly    93 VLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITPLAAHINYVV-----LIVVRVV 152
                |..|||:..:|...:...:..|       :|.|..|....|.....|.|     :..:|..
Yeast    81 ----FMIGYIVGMVPNNLMLLCVPPR-------IWLSFCTFAWGLLTLGMYKVTSFKHICAIRFF 134

  Fly   153 LGFMLGASWPAIHPVAAVWIP----PMERSKFM-SNMMASSLGAAITMPICGYL---ISVAGWAS 209
            .......::...|.|...|..    |:..:.|. |.::.|.....:...|..:|   ..:|||..
Yeast   135 QALFESCTFSGTHFVLGSWYKEDELPIRSAIFTGSGLVGSMFSGFMQTSIFTHLNGRNGLAGWRW 199

  Fly   210 VFYLTGAVGLLWSLAWFTFVYETPATHPRISAEER----------REIEEAIGTTTSKKRPSHVP 264
            :|.:...:.|  .:|.:.|:: .|....:.||..:          :|:..|.....::...:.:.
Yeast   200 LFIIDFCITL--PIAIYGFIF-FPGLPDQTSAVSKFSMTRYIFNEQELHYARRRLPARDESTRLD 261

  Fly   265 WGQLLCSPAV------W--AIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLGK 321
            |..:   |.|      |  :::...|....||                   ..|..|:......|
Yeast   262 WSTI---PRVLKRWHWWMFSLVWVLGGENLGF-------------------ASNSTFALWLQNQK 304

  Fly   322 YVMAVASSYLADYLRKKGTLSTTAT--------RKLFTTFALVIPGLLMIVQVFLGYDATWSVTI 378
            |.:|..::|.:. :...|.:||..:        |......::.|..:::||.|.:..|......:
Yeast   305 YTLAQRNNYPSG-IFAVGIVSTLCSAVYMSKIPRARHWHVSVFISLVMVIVAVLIRADPLNPKVV 368

  Fly   379 FSLALFAHGAVTAGYLGNGLDIAPNFGGTIFGLAN---------------TLSSFGGFLSTSMVG 428
            ||          |.|||.   :|.......|..||               :::.|.|.::.
Yeast   369 FS----------AQYLGG---VAYAGQAVFFSWANIICHADLQERAIVLASMNMFSGAVNA---- 416

  Fly   429 ALTYKDQSFHSWQIVF-------------WILAATYISAAVVFAILGSGELQ 467
                      .|.|:|             :.|.||.||:.:|..::.|.:::
Yeast   417 ----------WWSILFFASDMVPKFERGCYALLATAISSGIVSVVIRSLQIK 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	89/507 (18%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	77/444 (17%)
FEN2	NP_009957.1	MFS_FEN2_like	32..450	CDD:340885	88/497 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000