DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and slc17a7

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_001072608.1	Gene:	slc17a7 / 780064	XenbaseID:	XB-GENE-5742677	Length:	576	Species:	Xenopus tropicalis

Alignment Length:	473	Identity:	154/473 - (32%)
Similarity:	252/473 - (53%)	Gaps:	34/473 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GLQRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTAS 72
            ||.|       |.::.:::.|||.:::.:|.||.:|||.||..      |....||.
Frog    58 GLPR-------RYIIAIMSGLGFCISFGIRCNLGVAIVSMVNN------NTVYKGNK-------- 101

  Fly    73 PDGVDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITPL 137
               :.:.:.:|.||......:.|.||||||:|::|||.:.:.....||||.:::..|.|.::.|.
Frog   102 ---IVIEQAQFTWDPETVGMIHGSFFWGYIVTQIPGGYICQKFAANRVFGFAIVATSTLNMLIPS 163

  Fly   138 AAHINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMASS-LGAAITMPICGYL 201
            ||.:::..:|.||::.|.:.|.::||.|.:.:.|.||:|||:..:.....| .||.:.||:.|.|
Frog   164 AARVHFACVICVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVL 228

  Fly   202 ISVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGTTTSKKRPS---HV 263
            :..:||:||||:.|:.|::|.:.|....||:||.||.||.||::.|||:||.:|....|.   ..
Frog   229 VQYSGWSSVFYVYGSFGIMWYMFWILVSYESPAIHPTISEEEKKYIEESIGESTGLMNPMAKFKA 293

  Fly   264 PWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLGKYVMAVAS 328
            ||.:...|..|:|||:.:....:.|:.::...|.:..::..|:|.:.||.|:||:|...::....
Frog   294 PWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLLSALPHLVMTIIVPIG 358

  Fly   329 SYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSVTI--FSLALFAHGAVTA 391
            ..:||:||.|..:|||..||:.......:...|::|   :||..:..|.|  ..||:...|...:
Frog   359 GQIADFLRTKRIMSTTNVRKMMNCGGFGMEATLLLV---VGYSHSRGVAISFLVLAVGFSGFAIS 420

  Fly   392 GYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILAATYISAAV 456
            |:..|.|||||.:...:.|::|.:.:..|.:...:|||:| |.::...||.||.|.:..:....:
Frog   421 GFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMT-KHKTREEWQYVFLIASLVHYGGVL 484

  Fly   457 VFAILGSGELQPWNNPPE 474
            .:.|..|||.|||..|.|
Frog   485 FYGIFASGEKQPWAEPEE 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	151/462 (33%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	127/383 (33%)
slc17a7	NP_001072608.1	2A0114euk	62..503	CDD:129972	151/462 (33%)
		MFS	67..490	CDD:119392	142/443 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	517..547
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920