DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and slc17a5

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_001070195.1	Gene:	slc17a5 / 767760	ZFINID:	ZDB-GENE-060929-1158	Length:	488	Species:	Danio rerio

Alignment Length:	462	Identity:	163/462 - (35%)
Similarity:	261/462 - (56%)	Gaps:	24/462 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTAS---PDGVDV 78
            |.|..|..|:..||.:.|||||||::|:|||::             ||:.||:::|   |..:.|
Zfish    34 SSRYGLAFLSCYGFFVAYALRVNLSVAMVDMLK-------------NSSKANTSSSICPPHNIPV 85

  Fly    79 YEER-----FPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITPLA 138
            .:..     :.|:|....::||.||:|||:|::|||.||...|.:.:.|..:|...:.||:||||
Zfish    86 PKHNHTAMVYDWNSETQGWILGSFFYGYIITQIPGGYLARKYGAKWLLGLGILCTVIFTLLTPLA 150

  Fly   139 AHINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMS-NMMASSLGAAITMPICGYLI 202
            |.:....||.|||:.|...|.::||:|.:.|.|.||:|||:.:: :...:.||..:.:|:.|.:.
Zfish   151 ADLGAGYLIAVRVLEGIGEGVTYPAMHAMWASWAPPLERSRLLTISYTGAQLGTVVALPLSGQIC 215

  Fly   203 SVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGTTTSKKRPSHVPWGQ 267
            ....|..|||:.|||||||...|..||..:|::|.||:..|:..|..::....|..: .::||..
Zfish   216 FYLDWTYVFYIFGAVGLLWFFLWICFVSNSPSSHKRITEAEKTYIMSSLKNELSPTQ-DYIPWTS 279

  Fly   268 LLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLGKYVMAVASSYLA 332
            :..|..:|||::.|....:.|:|::..|||:|:.:|.|.|:|||:.|:|||||.:::|:....||
Zfish   280 IFKSMPLWAIVVAHFSYNWTFYTLLTLLPTYMNDVLGFSIQQNGMLSALPYLGCWLLALLGGQLA 344

  Fly   333 DYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSVTIFSLALFAHGAVTAGYLGNG 397
            |.||::....|...||.||...:..|.:.::...:.|.:...:|...:::....|...:|:..|.
Zfish   345 DLLRERFLFRTVIVRKAFTVVGMAGPAVFLVAAGYTGCNYILAVAFLTISSSLGGISASGFNINH 409

  Fly   398 LDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILAATYISAAVVFAILG 462
            |||||::.|.:.|:.|:.::..|.:...:..:|| |..:...|||||:|.||..|..||.|.|.|
Zfish   410 LDIAPSYAGILLGITNSFATIPGMVGPVIARSLT-KSNTIPEWQIVFYISAAINIFGAVFFTIFG 473

  Fly   463 SGELQPW 469
            .|.:|||
Zfish   474 KGTVQPW 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	162/460 (35%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	133/378 (35%)
slc17a5	NP_001070195.1	2A0114euk	27..488	CDD:129972	163/462 (35%)
slc17a5	NP_001070195.1	MFS	92..472	CDD:119392	133/381 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D378598at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920