DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3036 and Slc17a7

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_892038.2	Gene:	Slc17a7 / 72961	MGIID:	1920211	Length:	560	Species:	Mus musculus

Alignment Length:	474	Identity:	158/474 - (33%)
Similarity:	252/474 - (53%)	Gaps:	36/474 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GLQRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTAS 72
            ||.|       |.::.:::.|||.:::.:|.||.:|||.||.                  |||..
Mouse    58 GLPR-------RYIIAIMSGLGFCISFGIRCNLGVAIVSMVN------------------NSTTH 97

  Fly    73 PDG-VDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITP 136
            ..| |.|.:.:|.||......:.|.||||||:|::|||.:.:.....||||.:::..|.|.::.|
Mouse    98 RGGHVVVQKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIP 162

  Fly   137 LAAHINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMASS-LGAAITMPICGY 200
            .||.::|..:|.||::.|.:.|.::||.|.:.:.|.||:|||:..:.....| .||.:.||:.|.
Mouse   163 SAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGV 227

  Fly   201 LISVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGTTTSKKRP---SH 262
            |:..:||:||||:.|:.|:.|.|.|....||:||.||.||.|||:.||:|||.:.....|   .:
Mouse   228 LVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKLMNPVTKFN 292

  Fly   263 VPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLGKYVMAVA 327
            .||.:...|..|:|||:.:....:.|:.::...|.:..::..|:|.:.||.|:||:|...::...
Mouse   293 TPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLVMTIIVPI 357

  Fly   328 SSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSVTI--FSLALFAHGAVT 390
            ...:||:||.:..:|||..|||.......:...|::|   :||..:..|.|  ..||:...|...
Mouse   358 GGQIADFLRSRHIMSTTNVRKLMNCGGFGMEATLLLV---VGYSHSKGVAISFLVLAVGFSGFAI 419

  Fly   391 AGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILAATYISAA 455
            :|:..|.|||||.:...:.|::|.:.:..|.:...:|||:| |.::...||.||.|.:..:....
Mouse   420 SGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMT-KHKTREEWQYVFLIASLVHYGGV 483

  Fly   456 VVFAILGSGELQPWNNPPE 474
            :.:.:..|||.|||..|.|
Mouse   484 IFYGVFASGEKQPWAEPEE 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	155/463 (33%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	129/383 (34%)
Slc17a7	NP_892038.2	MFS_SLC17A6_7_8_VGluT	66..490	CDD:340940	146/445 (33%)
Slc17a7	NP_892038.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	497..560		3/6 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820