DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and MFS15

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_611375.2	Gene:	MFS15 / 37168	FlyBaseID:	FBgn0034392	Length:	497	Species:	Drosophila melanogaster

Alignment Length:	490	Identity:	147/490 - (30%)
Similarity:	250/490 - (51%)	Gaps:	55/490 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GLQRVRNF---LSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANS 69
            |.|::.|.   ...|.:..:|...|..:.|:|||||::|||.|...|
  Fly    13 GYQQIGNTGPRFGVRHLQCILVFFGLAVAYSLRVNLSVAIVAMTDRN------------------ 59

  Fly    70 TASPDGVDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLI 134
            .::||    :.| |.|:....:::|..|||||::|::|||.|:.:.|.:.:..:.:|..|.|.|:
  Fly    60 ASNPD----FPE-FDWNESTKSYLLSSFFWGYVVTQIPGGYLSAIYGAKYMLFYGVLICSCLALL 119

  Fly   135 TPLAAHIN--YVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMS-NMMASSLGAAITMP 196
            ||..| :|  :.|::|:|.|.|...|..:|:.|...:.|.|..||.:.:. ....|..|..:.:.
  Fly   120 TPFCA-VNGGWTVVVVLRAVQGLCQGVIFPSTHTFLSKWAPAEERGRLVGYTYSGSQFGTVVMLS 183

  Fly   197 ICGYLISVA-GWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGTTTSKKRP 260
            :.||:.|.: ||.|.||:.|.||::||..|......|||.||.|:..|||.||    ::...:||
  Fly   184 VSGYIASSSLGWPSTFYIPGCVGIVWSFVWLYLCSSTPAQHPTITPNERRFIE----SSGQARRP 244

  Fly   261 SH----------VPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSS 315
            |.          .||.::..|.....:::.|....:||:|::.::||||..:|..|||.||..|:
  Fly   245 SDAGREEQPRPPTPWWRIFTSVPFLVLVLAHCANNWGFWTLLTEIPTFMKNVLGMDIKNNGPLSA 309

  Fly   316 LPYLGKYVMAVASSYLADYLRKKGTLSTTA-TRKLFTTFALVIPGLLMIVQVFLGY------DAT 373
            |||....::.....:|:|.|:::||:.... :||.|.|..:.:|   |:..:.|||      :..
  Fly   310 LPYFAMILLTCVFIWLSDTLKQRGTVIPLGFSRKFFNTLGMWLP---MLALIGLGYITEGEANVR 371

  Fly   374 WSVTIFSLALFAHGAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFH 438
            .::.:.:.|:..:.|...|:..|.:|::||:.||:.|:.|..::|...|:..:||.:.:.:.:..
  Fly   372 LAIGLLTAAVATNSATYLGFHVNHIDLSPNYAGTLMGITNCAANFMSILAPLIVGLIVWDETNPA 436

  Fly   439 SWQIVFWILAATYISAAVVFAILGSGELQPWNNPP 473
            .|:|||:..|..|....::|.:.|...:||||:.|
  Fly   437 QWRIVFFFTAFVYFIGNLLFMLFGRTRVQPWNSRP 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	144/476 (30%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	121/398 (30%)
MFS15	NP_611375.2	2A0114euk	18..469	CDD:129972	143/481 (30%)
MFS15	NP_611375.2	MFS	31..459	CDD:119392	137/458 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970