DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and NaPi-T

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster

Alignment Length:	507	Identity:	168/507 - (33%)
Similarity:	276/507 - (54%)	Gaps:	38/507 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTASP------- 73
            :..|.||..:|.:||::||.:|:||.|.||||:      |....:..|.|..|||...
  Fly     4 VEARTVLWYMTFIGFIVNYMIRINLNITIVDMI------AGKGAITSNETHENSTDLAALAEMNE 62

  Fly    74 ---------DGVDV-YEER-FPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLW 127
                     |..:: ||:. |.|:..|...:||.|||.:...::|||.||...|.:.|||.|...
  Fly    63 RFSLERWFLDWANIPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGI 127

  Fly   128 ASLLTLITPLAAHINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMASSLGAA 192
            ......:.|:.::.:|..||::||..|::.|.:||::|.:.|.||||.|||||:|..:.||:|.|
  Fly   128 GVFCCFLIPIVSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFVSAYLGSSVGVA 192

  Fly   193 ITMPICGYLISVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGTT-TS 256
            :..||.||:|....|..|:|:.|.||.||.:||...|:::||.||||:..||:.||:::|.: ..
  Fly   193 LFYPIFGYIIDWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGASIQG 257

  Fly   257 KKRPSHVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLGK 321
            .|.|:  ||..:..|..||..::.....::|.||::...||:...|.|::|:..|..|.||:|.:
  Fly   258 SKGPT--PWKAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMR 320

  Fly   322 YVMAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSVTIFSLALFAH 386
            .:.|...|..||||.:...:|.|..|||.|.......||:::...:.||:||.::.:.::|...|
  Fly   321 MLFAYVFSIFADYLLRTDKMSRTNVRKLATFICCGTKGLIVLALAYFGYNATAAIVLVTVATMLH 385

  Fly   387 GAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILAATY 451
            |||::|.|.:.:|::||:.|.:.|::..:....||:|..:||.||:.:|:..:|:.||.:.:...
  Fly   386 GAVSSGPLASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVFLLTSLML 450

  Fly   452 ISAAVVFAILGSGELQPWNNPPERVRISDV-----------TQEEGVPLKNE 492
            ..:.:::.:....:|||||:...::..|.:           .:||..|||::
  Fly   451 TGSGILYVLFSESKLQPWNSGCHQLPDSGLKELQNLGRDQDDEEEKKPLKSD 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	162/476 (34%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	132/378 (35%)
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	162/477 (34%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	134/385 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970