DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and MFS12

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_610332.3	Gene:	MFS12 / 35745	FlyBaseID:	FBgn0033234	Length:	477	Species:	Drosophila melanogaster

Alignment Length:	474	Identity:	146/474 - (30%)
Similarity:	242/474 - (51%)	Gaps:	45/474 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GGLQRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTA 71
            ||| .||::.:      :|..:|.|:||..|||::.|||.|                      |.
  Fly    13 GGL-GVRHWQA------VLLFVGMMINYFQRVNISAAIVPM----------------------TQ 48

  Fly    72 SPDGVDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITP 136
            |..|...|    .||:...:.:|..|||||:::::|.|.||:..|.:.|.|.:.....:|....|
  Fly    49 STAGAPFY----TWDTSDKSLILSSFFWGYVVSQVPAGLLAKRFGAKLVLGLATAIGGILCFFHP 109

  Fly   137 LAAHINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMA-SSLGAAITMPICGY 200
            :||...:..:.|:||:.|.:.|..:|.:|.:.|.|:|..||....:.:.: :..|.|:.:...|:
  Fly   110 IAAKSGWQSICVLRVLTGLVQGTVYPCVHTLLAKWVPRTERGLLTTGVYSGAQFGTAVILVTSGF 174

  Fly   201 LI-SVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGT-TTSKKRPSHV 263
            :. |..||..:|||:|.:.|.|:|.:|......|.|..|||..|...||...|: ::|:..|  |
  Fly   175 IFESSMGWPGLFYLSGGLSLAWALLFFWQAANEPVTASRISKGEVEYIESLTGSNSSSQSMP--V 237

  Fly   264 PWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLGKYVMAVAS 328
            ||..:..|||.:.::..|....:||:|::.::||:||.:|..::|.|...|||||....::....
  Fly   238 PWMSIFRSPAFYGLLAAHCGFTWGFYTLLTEMPTYMSMVLQLNVKSNAFLSSLPYFAMGLLCFVV 302

  Fly   329 SYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGY----DATWSVTIFSLALFAHGAV 389
            |.::|.|..:||:|.|..||||.:.....|   |...:.|||    :.||::.:.:||:..:...
  Fly   303 SPISDLLINRGTISITTARKLFNSIGQWGP---MACLIGLGYMTADEKTWAILLLTLAVGINAGC 364

  Fly   390 TAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILAATYISA 454
            :.|||.|.:|::|||.|.:.|:.|.::.....::..:|||:...::....|::||:|....|:..
  Fly   365 SCGYLINHIDLSPNFAGPMMGVTNGIAGVTSIIAPLVVGAIVSDEEDPSQWRMVFFITGGIYLVC 429

  Fly   455 AVVFAILGSGELQPWNNPP 473
            ..:|.|.|...:|.||.||
  Fly   430 NTIFVIFGKATIQIWNEPP 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	141/462 (31%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	118/384 (31%)
MFS12	NP_610332.3	MFS	23..436	CDD:119392	134/443 (30%)
MFS12	NP_610332.3	2A0114euk	25..447	CDD:129972	138/452 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970