DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and CG9254

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_609664.1	Gene:	CG9254 / 34773	FlyBaseID:	FBgn0028513	Length:	481	Species:	Drosophila melanogaster

Alignment Length:	459	Identity:	143/459 - (31%)
Similarity:	249/459 - (54%)	Gaps:	24/459 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LLTMLGF--MLN-YALRVNLTIAI-VDMVRPNVTSAVNATLVGNSTAANSTASPDGVDVYEERFP 84
            :|.::||  :.| |.:|:.|:.|| |.:|:.|.|......:......::.:::.:|.|     :.
  Fly    25 ILAIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIFHTEAICEPDDQSDPSSTFEGGD-----YD 84

  Fly    85 WDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITPLAAHINY---VVL 146
            |...:...:|..|:.|||:|.||||.||:..||:......:.:.::.||:||:.  |.|   ..|
  Fly    85 WSQEKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVC--IVYGGADAL 147

  Fly   147 IVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMM-ASSLGAAITMPICGYLISVAGWASV 210
            ||:||::|...|.::||:..:.|.|:|..||....:.:: ...:|:.....|.||::|...|..|
  Fly   148 IVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYVLSSMDWPWV 212

  Fly   211 FYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGTTTSKKRPSHVPWGQLLCSPAVW 275
            ||:...:.|:|.:.:....:.:|.|||.|..|||..:.:.: ....|.:|. .|:..:|.|..:|
  Fly   213 FYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEERAFLAQEV-PPPDKNKPK-TPFFAILTSIPMW 275

  Fly   276 AII---ICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLGKYVMAVASSYLADYLRK 337
            |:|   |.|.   :||:.:|:.||.:||.:|.|.||.|||:|||||:..::|::.|..:||.:.|
  Fly   276 ALISAQIGHD---WGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTMWIMSLLSGCVADQMIK 337

  Fly   338 KGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSVTIFSLALFAHGAVTAGYLGNGLDIAP 402
            :..:|||.|||:.|..|...|.:.|:...:.|.:....|.:|::.:...|...||.....||::|
  Fly   338 RNCMSTTNTRKIMTGVAAFGPAVFMVAASYAGCNRGMVVALFTITMGLMGTYYAGMKLTPLDMSP 402

  Fly   403 NFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILAATYISAAVVFAILGSGELQ 467
            |:.||:..:.|.:.:..|.:|..:||.:| .:.:...|::|||:.....:..|:|:.|..||::|
  Fly   403 NYAGTLMAITNGIGAITGVVSPYLVGVMT-PNATLLEWRLVFWVAFGVLVVTAIVYCIWASGDVQ 466

  Fly   468 PWNN 471
            |:|:
  Fly   467 PFND 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	143/459 (31%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	122/384 (32%)
CG9254	NP_609664.1	2A0114euk	28..466	CDD:129972	139/450 (31%)
CG9254	NP_609664.1	MFS	82..461	CDD:119392	124/391 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.960