DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and MFS18

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_608835.1	Gene:	MFS18 / 33650	FlyBaseID:	FBgn0025684	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	467	Identity:	114/467 - (24%)
Similarity:	199/467 - (42%)	Gaps:	84/467 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTASPDGVDVYEERFPWD 86
            :.|:|  |..:.|:.|..:.:.:     |.|.||..                           |.
  Fly    31 ITLIT--GTCMLYSTRTTMPLLV-----PAVASAQK---------------------------WS 61

  Fly    87 SYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITP----LAAHI-NYVV- 145
            ...:..||..|||||.||::.||..::..||:||...:.:..||:|.:.|    .|..| :|.:
  Fly    62 KTDSGTVLSSFFWGYTLTQVVGGYFSDRFGGQRVILFAAIGWSLITFLMPTIIWTAGSIKSYAIP 126

  Fly   146 -LIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMA-SSLGAAITMPICGYLISVAGWA 208
             ::.:|::.|.:.|..:|::..:.:..:.|.|||.|...:.| |:||..:|..:..:|:...||:
  Fly   127 FIVAIRILNGALQGVHFPSMISLTSQNLCPNERSSFFGLLTAGSALGTLLTGIMGSFLLDYFGWS 191

  Fly   209 SVFYLTGAVGLLWSLA--WFTFVYE-----TPATHPRISAEERREIEEAIGTTTSKKRPSHVPWG 266
            .||.:.|.:|:.|:|.  ::....|     ..||..|:.|.:            |....|.|||.
  Fly   192 YVFRVIGLMGIAWALVLRYYAMAGERNRIINIATPSRLCANK------------SPAETSAVPWL 244

  Fly   267 QLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILH--FDIKQNGLFSSLPYLGKYVMAVASS 329
            :.....:.||.::.|...:..||.:::.|||:    .|  |...:..:.:.:|:|......:.:.
  Fly   245 RYFRRLSFWACVLTHACEMNCFFVLLSWLPTY----FHDGFPHAKGWVVNMIPWLALPPCTLFAK 305

  Fly   330 YLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSVTIFSLAL------FAHGA 388
            ||...|..: ...||..||:..:.......|.:.|   :...:.:...:..:.:      |.:.|
  Fly   306 YLTTRLLAR-EWHTTTVRKVIQSCCFAAQNLALFV---MSRTSDFHTALICMTIIIGGTGFHNNA 366

  Fly   389 VTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILAATYIS 453
            ||.    |..|:||...|::|||.||:.:..|||...:.|.:....|   ||.:||...|...:.
  Fly   367 VTV----NPQDLAPLHSGSVFGLMNTVGAIPGFLGVYLAGHILELTQ---SWPMVFSAAAGINLV 424

  Fly   454 AAVVFAILGSGE 465
            ..::|.:.||.|
  Fly   425 GWIIFIVFGSAE 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	114/467 (24%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	102/400 (26%)
MFS18	NP_608835.1	MFS	30..432	CDD:119392	111/461 (24%)
MFS18	NP_608835.1	MFS_1	32..397	CDD:284993	102/422 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.960