DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and SPAC11D3.18c

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_001342807.1	Gene:	SPAC11D3.18c / 2543005	PomBaseID:	SPAC11D3.18c	Length:	498	Species:	Schizosaccharomyces pombe

Alignment Length:	482	Identity:	101/482 - (20%)
Similarity:	178/482 - (36%)	Gaps:	130/482 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTASPDG 75
            :|...|..:..|.:..::||:        ..:|.:|  |.|         :||:..|..|   :.
pombe    48 KVEKKLLLKMDLVISPIIGFL--------YLMAFLD--RSN---------IGNAAVAGMT---EA 90

  Fly    76 VDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGH-SMLWASLLTLITPLAA 139
            :.:|.||.       |..:..|:..|||.|.|...|.:.|...|:... |..| |:..|.:...:
pombe    91 LSLYGERL-------NVAVSIFYVLYILVETPSVVLVKRIKASRMLAFISFAW-SMTVLFSGFMS 147

  Fly   140 HINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMASS-LGAAITMPICGYLIS 203
              :|..||..|::||.:.|..:||::..........|:.:.:|.:.||: |..|.     |.|.:
pombe   148 --SYGGLIATRLILGLLEGCLFPALNLYLTTHYTRKEQCQRLSYLFASAGLAGAF-----GGLFA 205

  Fly   204 VA----------GWASVFYLTGAVGL------LWSL------AWFTFVYETPATHPRISAEERRE 246
            .|          ||..::.:.|.|..      |::|      |||            ::.|||
pombe   206 YALEQVHAGNKEGWQWIYIVEGLVSFIGVPLCLFALPDKMENAWF------------LTREER-- 256

  Fly   247 IEEAIGTTTSKKR---PSHVPWGQL---LCSPAVWAII---ICHGLAVFGFFTVVNQLPTFMSKI 302
             |.||.......|   ..|..|.::   ...|.|:...   .|..:.::||.:.   ||..:..:
pombe   257 -EVAIIRRDINARYHGEQHFEWSEVRKAFKDPKVYVSATSQFCADMVLYGFSSF---LPVIIKGL 317

  Fly   303 LHFDIKQNGLFSSLPYLGKYVMAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQV- 366
            ....::.|  :.::|.   |:..|.|.....:|..:     |..|.::...|..:..:..|:.:
pombe   318 GFVGLQTN--YMTIPV---YIAGVISFLFVAWLSDR-----TQLRAVYLISASTVVAVGYIIMLA 372

  Fly   367 ----FLGYDATWSVTIFSLALFAHGAVTAGYLGNGLDIAPNF-GGTIFGLANTLSSFGGF----- 421
                ...|.||:   |.::..:....:..|:|.|  ::|.:: ..|..|:..||::..|.
pombe   373 SDSNAAKYTATY---IIAIGCYIGPGLNLGWLNN--NVAGHYKRATAIGIQQTLANSSGIVAGQI 432

  Fly   422 ----------------LSTSMVGALTY 432
                            |...:||.|.|
pombe   433 YRSKNAPKYILGNAFTLGCVIVGGLAY 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	99/474 (21%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	85/410 (21%)
SPAC11D3.18c	NP_001342807.1	UhpC	68..461	CDD:332119	96/462 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050