DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3036 and vht1

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_594801.1	Gene:	vht1 / 2542518	PomBaseID:	SPAC1B3.16c	Length:	568	Species:	Schizosaccharomyces pombe

Alignment Length:	542	Identity:	104/542 - (19%)
Similarity:	187/542 - (34%)	Gaps:	160/542 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SNTEKGGLQRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTA 66
            :::|...||::|..:..| ::..|.:| :.|:..||..::::.      .:.:|...:|:
pombe    67 TSSELRRLQKLRLKMDLR-IIPCLWIL-YFLSCCLRFTVSLSF------TMNTAQGHSLI----- 118

  Fly    67 ANSTASPDGVDVYEERFPWDSYQTNFV---LGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWA 128
              .|.|              .|..:::   |..|:.|||:.|:|...:...|..|       :|.
pombe   119 --QTLS--------------GYSAHYLALGLALFYVGYIIFEVPSNLMMAFIEPR-------IWV 160

  Fly   129 SLLTLITPLAA---------HINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNM 184
            |.:.|...:..         |.|....:.:|..||......||.:....:.|.    |.|.:...
pombe   161 SRIQLTIGVVGACHAVLGTKHGNAQSYVALRFFLGVAESGLWPGLAYYMSRWY----RGKHLGKR 221

  Fly   185 M------ASSLGAAITMPICGY-----LISVAGWASVFYLTGAVGLLWSLA--WFTFVYETPATH 236
            :      |....||:::...|:     ...:.|:..:|.:.|.|.:..:|:  |:.
pombe   222 IGWYYTAAQIAAAAVSLVSAGFQKMDGARGLYGYQWMFLIWGVVAIAQALSIPWWL--------- 277

  Fly   237 PRISAEERRE---------------IEEAIGTTTSKKRPSHV------------PWGQLLCS--- 271
            |.::::|.|:               ..:.||..|...:..|.            .|..||.|
pombe   278 PAVASKEHRKSLSSFIPLPKWMKTLSPQRIGFLTPADKSLHSRYIAEMNVGKRWQWSDLLKSCLD 342

  Fly   272 PAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLGKYVMAVASSYLADYLR 336
            ..||..|:.:    ||...|.|.:..:.:.|:.   :.|..||.:    ...:..|..:|||.|
pombe   343 LRVWPFILMY----FGIVGVGNGIFNYCTLIIE---EINPSFSGI----DISLLNAPIWLADAL- 395

  Fly   337 KKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSVTIFSLALFAHGAVTAGYLGNGLDIA 401
                                  |::.::.::..:...:|....|..:...|...|.|       |
pombe   396 ----------------------GIVTVMPLYDRFHKKFSFFTGSCLIIIAGLAVANY-------A 431

  Fly   402 P----NFGGTI---FGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILAATYISAAVVFA 459
            |    .:||.:   |||..|:.....:.|.||  |.||.|....|  .:..:.....:.:.|...
pombe   432 PRAWSRYGGLLMIGFGLGPTVPICMAWCSASM--AKTYGDVGVAS--SLALVTGLGNLGSVVTTY 492

  Fly   460 ILGSGELQPWNNPPERVRISDV 481
            .|.||    |...|...:.:||
pombe   493 ALYSG----WPGDPTFRKSNDV 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	98/519 (19%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	83/439 (19%)
vht1	NP_594801.1	HpaX	80..503	CDD:131385	97/520 (19%)
vht1	NP_594801.1	MFS	94..493	CDD:119392	90/490 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000