Protein Alignment CG3036 and Slc17a5

DIOPT Version :10

• Sequence 1: NP_608873.1
• Gene: CG3036 / 33695
• FlyBaseID: FBgn0031645
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_766361.1
• Gene: Slc17a5 / 235504
• MGIID: 1924105
• Length: 495
• Species: Mus musculus
• Alignment Length: 654
• Identity: 120/654 - (18%)
• Similarity: 206/654 - (31%)
• Gaps: 231/654 - (35%)

  Fly   436 FRGEKCISYTGEITGGIAGGALLLLGVVSLVLYRNWRYEQELDSLLWKVDFREIQMHENEKETAG 500
            |.|...:|.:||          .|...|.|:....||.....|..|.:.....:::.|:..:...
Mouse    70 FSGSSTVSSSGE----------RLSPDVVLLFSGRWRSSVAPDDQLQEALRTRLRVVESNSQDVV 124

  Fly   501 QKMTRVSVCVCRSHA----------------YYSTH----------------------PLIRTSQ 527
            |....:|..:...||                .:||:                      |.: .|.
Mouse   125 QLFKDLSARLLSVHAEKDSFVITFKTVEEIWKFSTYLALGYVARCLENFLCDQSFWLDPAL-LSD 188

  Fly   528 VSLSSNPDLDFRYSTIFTPIGLYKGQLYAIKKVKKKSIDITREMKKELKLLRDMRHDNLNAFIGA 592
            |.:|...|.| ..:|::..:.|.:|..:. |.:.|..   .:|.::||...|:
Mouse   189 VEISVTVDED-HLATLYLGLLLQEGTFFG-KTLYKSD---CKEEEEELNYRRN------------ 236

  Fly   593 CTDPPNICIITDYCNRGSLKDVLENEDVKLDNMFTASMVADILRGMIYLHDS---PLRFH----- 649
                                |::..:|:..:.::..::::....|::.:||.   |..|:
Mouse   237 --------------------DLVMVKDIGQEAIWEGTLLSTGKHGLVPVHDMQPLPYPFYQWFLK 281

  Fly   650 ------GSLRTSNCLIDSRWVV-------------------------KLSDF------------- 670
                  |.:..:..|.|...||                         |:..|
Mouse   282 KYPGNAGGISVTEGLFDHPVVVGTCVAVVDHYPVVKDELHLRIGDQIKIEGFLFNTLSMFIGRHL 346

  Fly   671 --GLFAFKQGSEEVPDEKEKL--------EEKCQKLLYRAP--ELLRAGPTATVPGTPKGDVYSF 723
              |...|...:...|:..|:|        ||:...|....|  |..:|.....:..|....||..
Mouse   347 TSGETGFVHKAHVKPESTERLNGQLVFLSEEERTALSKLNPCLEPSQADVLTNLFSTDISTVYRL 411

  Fly   724 GIVLYEIFT--RRGPFGEIECTPMECLKRVLNPLDPNTPFRPAIQPLET---------------S 771
            ..:....||  |..|..| :.|.::..||.::.....||:..:  |.::               |
Mouse   412 DRLDDSDFTYIRNHPIPE-QKTTVDQRKRTVSEKSDATPYHSS--PRQSFSASRNHLDRDSEVLS 473

  Fly   772 FDCVRDCLKECWAERPEDRPDFK-----------------TIRNRLRVLRKGMRPNIFDNMMAMM 819
            |: :.|..:| ..|..||.|:|.                 |:.| |...:...| .::|...:.:
Mouse   474 FN-LEDTFRE-MDEYEEDPPNFMDEGIWETEEAERCDPILTLLN-LEYFQDTFR-TLYDLSYSFL 534

  Fly   820 EKYANNL-EQLVDERTDQLQEEKKKTEALLLE-----MLPRPVAEQLKRGHKVEAESYDLVTIYF 878
            :.:.|.| |..|.:..:.|:|..||...|...     :|.|..|::||         |....:||
Mouse   535 DTFFNGLPEDEVLQHLENLREGAKKGRMLWAHRRACFLLGRLCAKKLK---------YSQARVYF 590

  Fly   879 SDIVGFTSMSAESTPLQVVDFLND------LYTCFDSIIGHYDVYKVE-----TIGDAYMVVSGL 932
            .:        |...|   |:..||      |||...|:   |...|:.     |:..|..::..|
Mouse   591 EE--------ASKVP---VNGFNDKPLLIALYTNLTSV---YLKQKMMDKLPFTLEKASALILCL 641

  Fly   933 PIRN 936
            |..|
Mouse   642 PCHN 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_608873.1	MFS_SLC17	24..462	CDD:340876	6/25 (24%)
Slc17a5	NP_766361.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		Dileucine internalization motif. /evidence=ECO:0000250|UniProtKB:Q9NRA2	22..23
		MFS_SLC17A5	42..478	CDD:340939	75/459 (16%)