DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and Slc17a8

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_892004.1	Gene:	Slc17a8 / 216227	MGIID:	3039629	Length:	601	Species:	Mus musculus

Alignment Length:	467	Identity:	153/467 - (32%)
Similarity:	245/467 - (52%)	Gaps:	33/467 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SC-----RQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTASPDG- 75
            ||     |.::.:::.|||.:::.:|.||.:|||:||.                  |||...||
Mouse    81 SCCGIPKRYIIAVMSGLGFCISFGIRCNLGVAIVEMVN------------------NSTVYVDGK 127

  Fly    76 VDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITPLAAH 140
            .::...:|.||......:.|.||||||:|::|||.::......||||.::...|.|.:..|.||.
Mouse   128 PEIQTAQFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKFAASRVFGAAIFLTSTLNMFIPSAAR 192

  Fly   141 INYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMASS-LGAAITMPICGYLISV 204
            ::|..::.||::.|.:.|.::||.|.:.:.|.||:|||:..:.....| .||.:.||:.|.|:..
Mouse   193 VHYGCVMGVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQY 257

  Fly   205 AGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGTTTSKKRPS--HVPWGQ 267
            .|||||||:.|..|::|.:.|....||.||.||.||..||..||.:||...:....|  :.||.:
Mouse   258 IGWASVFYIYGMFGIIWYMFWLLQAYECPAAHPTISNAERTYIETSIGEGANLASLSKFNTPWRR 322

  Fly   268 LLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLGKYVMAVASSYLA 332
            ...|..|:|||:.:....:.|:.::...|.:..::..|.|.:.||.|::|::...::......||
Mouse   323 FFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLA 387

  Fly   333 DYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSVTI--FSLALFAHGAVTAGYLG 395
            ||||.:..|:|||.||:.......:...|::|   :|:..|..|.|  ..||:...|...:|:..
Mouse   388 DYLRSRKILTTTAVRKIMNCGGFGMEATLLLV---VGFSHTKGVAISFLVLAVGFSGFAISGFNV 449

  Fly   396 NGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILAATYISAAVVFAI 460
            |.|||||.:...:.|::|.:.:..|.:...:|||:| |.::...||.||.|.|..:.|..:.:.:
Mouse   450 NHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMT-KHKTREEWQNVFLIAALVHYSGVIFYGV 513

  Fly   461 LGSGELQPWNNP 472
            ..|||.|.|.:|
Mouse   514 FASGEKQDWADP 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	151/460 (33%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	128/382 (34%)
Slc17a8	NP_892004.1	2A0114euk	88..526	CDD:129972	151/460 (33%)
		MFS	93..515	CDD:119392	144/443 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	576..601
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820