DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and slc-17.7

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_505399.1	Gene:	slc-17.7 / 179308	WormBaseID:	WBGene00022788	Length:	506	Species:	Caenorhabditis elegans

Alignment Length:	523	Identity:	129/523 - (24%)
Similarity:	218/523 - (41%)	Gaps:	91/523 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTASPDGVDV--- 78
            ||    :|.::....|...:.:.|.:.|..::|.|:..|:...|       ||||..||..:
Worm     4 SC----DLWSLRSVRLRVVIAIALALTIEGLMRSNLNMAIVCML-------NSTALTDGKPMIAS 57

  Fly    79 ----YEERFP--------------------WDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRR 119
                .|...|                    |.|.....:...|:.|.::..|....|...||..|
Worm    58 LNTSIEPATPLCPLLQFGESKVVEHKGTIFWTSQDRAIIFAAFYAGGLVATLASEVLNRYIGATR 122

  Fly   120 VFGHSMLWASLL----TLITP-LAAHINY--VVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMER 177
                |:|:..:.    |.:|| :|:..|:  ..:|::|.|:||..|..||.:..:.|.|.|..|:
Worm   123 ----SVLYGGIANVVGTFLTPFVASQTNFGTFPIILLRFVMGFGQGVLWPCMLVLIAQWFPVNEK 183

  Fly   178 SKFMS-----NMMASSLGAAITMPICGYLISVAGWASVFYLTGAVGLLWSLAWFTFVYETPA-TH 236
            |..::     |.::..:....|..:|..   ..||...|::....|::..:.|:..||::|. ..
Worm   184 STALAIATTGNQLSVVIAMFATAELCQL---PWGWPMAFHVYAVCGIVMCIIWYMMVYDSPCHAD 245

  Fly   237 PRISAEERREIEEAIGTTTSKKRPSHVPWGQLLCSPAVWAII---ICHGLAVFGFFTVVNQLPTF 298
            .::|.:|...|.    |...:.||.|..|..|:.||.||||.   ..|.....|   .:..||.:
Worm   246 KKLSRDELHYIT----TERVRLRPQHPNWMALMKSPVVWAIAASSFAHNYVTVG---TITYLPLY 303

  Fly   299 MSKILHFDIKQNGLFSSLPYLGKYVMAVASSYLADYLRKKGTLSTTATRKL---FTTFALVIP-G 359
            ...:|:..:..|||:|:||::.:.:..|..:.:|:..||:.........|.   ..:|.:.|. |
Worm   304 YKTVLNMSLTSNGLWSALPFVLQLISKVFYAGMAESARKRDWSDINRITKFCNSSASFGIAICFG 368

  Fly   360 LLMIVQVFLGYDATWSVTIFSLAL---FAHGAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGF 421
            ||.:...     :.....||.:.|   |..|.: .||..:.:.|||   |....:| ..|.|.|.
Worm   369 LLCLCDC-----SQRGAAIFLICLAMCFVSGYI-PGYNTSAVTIAP---GQTAAIA-AFSRFWGQ 423

  Fly   422 LSTSM----VGALTYKDQSFHSWQIVFWILAATYISAAVVFAILGSGELQPWNNPPERVRISDVT 482
            :::|:    :||.| |..:...|:|||.::||..:...:.|...|:..||.|::...:..| :|.
Worm   424 IASSVAPYHIGAYT-KQGTADEWKIVFAVIAAICVVTGIFFQCCGTASLQDWDSTHSKAPI-EVA 486

  Fly   483 QEE 485
            :||
Worm   487 REE 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	123/511 (24%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	104/424 (25%)
slc-17.7	NP_505399.1	MFS	31..467	CDD:391944	115/467 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930