DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and T27D12.1

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_001254320.1	Gene:	T27D12.1 / 174820	WormBaseID:	WBGene00012085	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	486	Identity:	125/486 - (25%)
Similarity:	204/486 - (41%)	Gaps:	54/486 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 VLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTASPDGVDVYEERFPW 85
            ||.||.:.....| .|..|..:..:|    :..|.:.|:|.|.:...:.|
Worm    39 VLILLCLTSIWSN-ILAFNFAVVCMD----DDDSEMGASLNGTARKTHFT--------------- 83

  Fly    86 DSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITPLAAHINYVVLIVVR 150
             |.|.:..:.......:|...|..:|..::|.|.||....:.:::.||:.||:..:.:...:.||
Worm    84 -STQNSLAMAIVAIAALLGNFPIVQLVGMVGIRTVFAGLGILSAVSTLLIPLSIRMGFYYFLAVR 147

  Fly   151 VVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMA-SSLGAAITMPICGYLISVAGWASVFYLT 214
            .:.||...|::|.|....|.|....:...|:|:::| ..|..|||||..|.|.|...|.|:||..
Worm   148 FLQGFAFAANFPVIGSFCAKWSYFKQNGLFVSSLVAYVQLSPAITMPASGALCSAFKWPSIFYAH 212

  Fly   215 GAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGTTTSKKRPSHVPWGQLLCSPAVWAIII 279
            |||.||..:.:..|...:|..||.:...|.::|.........|:....||:|.:|.:||:||:.:
Worm   213 GAVSLLLFVTYALFYRNSPQKHPFVGNVELKKISIGKIAAVDKRALKKVPYGPILKTPAIWAVWV 277

  Fly   280 CHGLAVFGFFTVVNQL----PTFMSKILHFDIKQNGLFSSLP----YLGKYVMAVASSYLADYLR 336
                |..|.||.||.:    |.::||:|.|.:...|:.:::|    :..|.:...||..|.
Worm   278 ----AAIGNFTCVNMMFLFSPIYLSKVLGFPVHSTGITAAIPPFLQFSSKLICGAASDRLT---- 334

  Fly   337 KKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYD-ATWSVTIFSLALFAHGAVTAGYLGNGLDI 400
               .||.....:||.|.|.|.....:.|..|:|.: ...::.:...|....||.|.|:...|..:
Worm   335 ---CLSEGVKFRLFNTLAFVGSAGFLCVLAFMGDEHKRNNMIVLGCAAAMLGATTGGFFKAGPVL 396

  Fly   401 APNF-----GGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILAATYISAAVVFAI 460
            :..:     |....|:..|:     .:....|.||| .:.:...|:.||.|..|..:...:.|.|
Worm   397 SKQYSHFVTGNISLGITITM-----LIVPFFVNALT-PNNTQEEWKYVFLITGAVMVITNIFFVI 455

  Fly   461 LGSGELQPWNNPPERVRISDVTQEEGVPLKN 491
            ...|:...|.:.... |.|.|...|...::|
Worm   456 FVRGDPCEWTSDSFH-RASSVADFEQHHIRN 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	120/470 (26%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	104/392 (27%)
T27D12.1	NP_001254320.1	MFS	56..456	CDD:391944	111/436 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920