DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3036 and Slc17a7

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	XP_038966881.1	Gene:	Slc17a7 / 116638	RGDID:	620101	Length:	585	Species:	Rattus norvegicus

Alignment Length:	481	Identity:	158/481 - (32%)
Similarity:	255/481 - (53%)	Gaps:	25/481 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 GLQRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVG---NSTAANS 69
            ||.|       |.::.:::.|||.:::.:|.||.:|||.||..:.|......:|.   .|.....
  Rat    58 GLPR-------RYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTTHRGGHVVVQTPYRSVHKQE 115

  Fly    70 TASP-----DGVDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWAS 129
            ..:|     .|.|..:.:|.||......:.|.||||||:|::|||.:.:.....||||.:::..|
  Rat   116 AVTPTVGDIQGGDTEKAQFNWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATS 180

  Fly   130 LLTLITPLAAHINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMASS-LGAAI 193
            .|.::.|.||.::|..:|.||::.|.:.|.::||.|.:.:.|.||:|||:..:.....| .||.:
  Rat   181 TLNMLIPSAARVHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVV 245

  Fly   194 TMPICGYLISVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGTTTSKK 258
            .||:.|.|:..:||:||||:.|:.|:.|.|.|....||:||.||.||.|||:.||:|||.:....
  Rat   246 AMPLAGVLVQYSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAIGESAKLM 310

  Fly   259 RP---SHVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLG 320
            .|   .:.||.:...|..|:|||:.:....:.|:.::...|.:..::..|:|.:.||.|:||:|.
  Rat   311 NPVTKFNTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLVSALPHLV 375

  Fly   321 KYVMAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSVTI--FSLAL 383
            ..::......:||:||.:..:|||..|||.......:...|::|   :||..:..|.|  ..||:
  Rat   376 MTIIVPIGGQIADFLRSRHIMSTTNVRKLMNCGGFGMEATLLLV---VGYSHSKGVAISFLVLAV 437

  Fly   384 FAHGAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILA 448
            ...|...:|:..|.|||||.:...:.|::|.:.:..|.:...:|||:| |.::...||.||.|.:
  Rat   438 GFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMT-KHKTREEWQYVFLIAS 501

  Fly   449 ATYISAAVVFAILGSGELQPWNNPPE 474
            ..:....:.:.:..|||.|||..|.|
  Rat   502 LVHYGGVIFYGVFASGEKQPWAEPEE 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	155/470 (33%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	129/383 (34%)
Slc17a7	XP_038966881.1	MFS_SLC17A6_7_8_VGluT	66..515	CDD:340940	146/452 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920