DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3036 and SLC17A3

DIOPT Version :9

Sequence 1:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_001091956.1	Gene:	SLC17A3 / 10786	HGNCID:	10931	Length:	498	Species:	Homo sapiens

Alignment Length:	503	Identity:	151/503 - (30%)
Similarity:	231/503 - (45%)	Gaps:	67/503 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 QRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNA-----------TLVGN 63
            ::|.:..|.|..:.|:.........|..|.:.|.:|.||  |.||..:.           :..|.
Human    29 RKVPSLCSARYGIALVLHFCNFTTIAQNVIMNITMVAMV--NSTSPQSQLNDSSEVLPVDSFGGL 91

  Fly    64 STAANSTASPDGVDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWA 128
            |.|..|.  |....||:    |.......:.|...:|.|||..|.|.||..:|.:||.|.|:...
Human    92 SKAPKSL--PAKAPVYD----WSPQIQGIIFGAVGYGGILTMAPSGYLAGRVGTKRVVGISLFAT 150

  Fly   129 SLLTLITPLAAHINYVVLIVVRVVLGF----MLG---ASWPAIHPVAAVWIPPMERSKFMSNMMA 186
            |.|||..|||.....|:|||.|:|.|.    :||   |.|..       |.||.|||:..|..::
Human   151 SFLTLCIPLATDFGIVLLIVTRIVQGLSQSSILGGQFAIWEK-------WGPPQERSRLCSIALS 208

  Fly   187 SS-LGAAITMPICGYLISVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERR----E 246
            .. ||....:.|.|::....||..|||:.|.||.:..|.||..:|:.|.::|.||..|:.    .
Human   209 GMLLGCFTAILIGGFISETLGWPFVFYIFGGVGCVCCLLWFVVIYDDPVSYPWISTSEKEYIISS 273

  Fly   247 IEEAIGTTTSKKRPSHVPWGQLLCSPAVWAIIICHGLAVFGFF-------TVVNQLPTFMSKILH 304
            :::.:|   |.|:|  :|...:|.|..:|:|.:       |.|       |:|..:||::|.:.|
Human   274 LKQQVG---SSKQP--LPIKAMLRSLPIWSICL-------GCFSHQWLVSTMVVYIPTYISSVYH 326

  Fly   305 FDIKQNGLFSSLPYLGKYVMAVASSYLADY-LRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFL 368
            .:|:.|||.|:||::..:|:.:...||||: |.||..|.|  .||:.|... .:|...:||.  |
Human   327 VNIRDNGLLSALPFIVAWVIGMVGGYLADFLLTKKFRLIT--VRKIATILG-SLPSSALIVS--L 386

  Fly   369 GYDATWSVTIFSLALFAHGAVT---AGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGAL 430
            .|..:..:|..:|...:.|..|   :|...|.|||||.:...:.|.:...||....:..::.|.|
Human   387 PYLNSGYITATALLTLSCGLSTLCQSGIYINVLDIAPRYSSFLMGASRGFSSIAPVIVPTVSGFL 451

  Fly   431 TYKDQSFHSWQIVFWILAATYISAAVVFAILGSGELQPWNNPPERVRI 478
            ..:|..| .|:.||::|.|..:...:.:.|.|..::|.|....:..|:
Human   452 LSQDPEF-GWRNVFFLLFAVNLLGLLFYLIFGEADVQEWAKERKLTRL 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	148/491 (30%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	126/400 (32%)
SLC17A3	NP_001091956.1	2A0114euk	23..497	CDD:129972	150/500 (30%)
SLC17A3	NP_001091956.1	MFS	98..481	CDD:119392	129/413 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820