Protein Alignment CG3036 and SLC17A3

DIOPT Version :10

• Sequence 1: NP_608873.1
• Gene: CG3036 / 33695
• FlyBaseID: FBgn0031645
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001091956.1
• Gene: SLC17A3 / 10786
• HGNCID: 10931
• Length: 498
• Species: Homo sapiens
• Alignment Length: 503
• Identity: 151/503 - (30%)
• Similarity: 231/503 - (45%)
• Gaps: 67/503 - (13%)

  Fly    10 QRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNA-----------TLVGN 63
            ::|.:..|.|..:.|:.........|..|.:.|.:|.||  |.||..:.           :..|.
Human    29 RKVPSLCSARYGIALVLHFCNFTTIAQNVIMNITMVAMV--NSTSPQSQLNDSSEVLPVDSFGGL 91

  Fly    64 STAANSTASPDGVDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWA 128
            |.|..|.  |....||:    |.......:.|...:|.|||..|.|.||..:|.:||.|.|:...
Human    92 SKAPKSL--PAKAPVYD----WSPQIQGIIFGAVGYGGILTMAPSGYLAGRVGTKRVVGISLFAT 150

  Fly   129 SLLTLITPLAAHINYVVLIVVRVVLGF----MLG---ASWPAIHPVAAVWIPPMERSKFMSNMMA 186
            |.|||..|||.....|:|||.|:|.|.    :||   |.|..       |.||.|||:..|..::
Human   151 SFLTLCIPLATDFGIVLLIVTRIVQGLSQSSILGGQFAIWEK-------WGPPQERSRLCSIALS 208

  Fly   187 SS-LGAAITMPICGYLISVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERR----E 246
            .. ||....:.|.|::....||..|||:.|.||.:..|.||..:|:.|.::|.||..|:.    .
Human   209 GMLLGCFTAILIGGFISETLGWPFVFYIFGGVGCVCCLLWFVVIYDDPVSYPWISTSEKEYIISS 273

  Fly   247 IEEAIGTTTSKKRPSHVPWGQLLCSPAVWAIIICHGLAVFGFF-------TVVNQLPTFMSKILH 304
            :::.:|   |.|:|  :|...:|.|..:|:|.:       |.|       |:|..:||::|.:.|
Human   274 LKQQVG---SSKQP--LPIKAMLRSLPIWSICL-------GCFSHQWLVSTMVVYIPTYISSVYH 326

  Fly   305 FDIKQNGLFSSLPYLGKYVMAVASSYLADY-LRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFL 368
            .:|:.|||.|:||::..:|:.:...||||: |.||..|.|  .||:.|... .:|...:||.  |
Human   327 VNIRDNGLLSALPFIVAWVIGMVGGYLADFLLTKKFRLIT--VRKIATILG-SLPSSALIVS--L 386

  Fly   369 GYDATWSVTIFSLALFAHGAVT---AGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGAL 430
            .|..:..:|..:|...:.|..|   :|...|.|||||.:...:.|.:...||....:..::.|.|
Human   387 PYLNSGYITATALLTLSCGLSTLCQSGIYINVLDIAPRYSSFLMGASRGFSSIAPVIVPTVSGFL 451

  Fly   431 TYKDQSFHSWQIVFWILAATYISAAVVFAILGSGELQPWNNPPERVRI 478
            ..:|..| .|:.||::|.|..:...:.:.|.|..::|.|....:..|:
Human   452 LSQDPEF-GWRNVFFLLFAVNLLGLLFYLIFGEADVQEWAKERKLTRL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3036	NP_608873.1	MFS_SLC17	24..462	CDD:340876	144/471 (31%)
SLC17A3	NP_001091956.1	MFS_SLC17	42..482	CDD:340876	144/472 (31%)