DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3008 and riok-1

DIOPT Version :9

Sequence 1:	NP_608871.1	Gene:	CG3008 / 33693	FlyBaseID:	FBgn0031643	Length:	603	Species:	Drosophila melanogaster
Sequence 2:	NP_001021570.2	Gene:	riok-1 / 171883	WormBaseID:	WBGene00019698	Length:	506	Species:	Caenorhabditis elegans

Alignment Length:	505	Identity:	155/505 - (30%)
Similarity:	244/505 - (48%)	Gaps:	91/505 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 KQSKVTVTLNKFLRDGDAEFLHDTAEDDYEEDELEQQKHDWDRFEDNERQLDSIPRCGFKVNKEG 190
            |...:.:.:...|.|.|.:....:::|:.|:..::|:|.:                .|.::.::.
Worm     3 KVEHLNLNIQNILEDVDIDTASSSSDDEPEQAVVKQEKLE----------------AGEQIEEQY 51

  Fly   191 EMITKHDPQLCAVRNAQRVMSFPPEFPTGDAAGFDMKLS-------------NKVFNQLRAHSRR 242
            :..:.:|..:.....|           |||   |..||:             |::...:..|:..
Worm    52 DTDSDYDDDIVEFAEA-----------TGD---FTKKLNAARLNTIGPNAARNRLTVDVERHADT 102

  Fly   243 GRSDKHEKV------ATAEMGLDAGTRLLLYKLINNQILEQINGIISTGKEAVILHANSDANYTG 301
            ....|.::|      ||.|..||..|||:|::|:....|..|:|.|||||||.:.||      ||
Worm   103 SEDRKRKRVKDRADRATVEQVLDPRTRLVLFRLLQRGTLLNIDGCISTGKEANVYHA------TG 161

  Fly   302 SNEHGHQSGVLVPPQLLPRECAIKIFKTTLNEFKQRDRYIKDDYRFKDRFSKQNHRVIINMWAEK 366
            ::                .:.||||:||::..||.|:||:..::|::..:.|.|.|.::.:||||
Worm   162 TD----------------NDLAIKIYKTSILTFKDRERYVTGEFRYRHGYCKSNPRKMVAVWAEK 210

  Fly   367 EMHNLMRMQAIGLNVPDVVVLKKHVLVMRFIGDNHNAAPKLKDARLSDAELSCAYEEIVAAMHKL 431
            ||.||.||..:||.||...:||.|||||.|:|.:...||.||:|.||..:....|..:|..|.:|
Worm   211 EMRNLARMHEVGLPVPKPHLLKGHVLVMDFLGKDGWPAPLLKNANLSQEDAEPMYVGLVRDMRRL 275

  Fly   432 YNEAKLVHADMSEYNILWFEGKCWFIDVAQSVEPKHPSALEFLMRDCGNIVNFFERRGLPNIYTK 496
            |.|.||||||:||:|:|..:||.|.|||:||||..||.|||||..||.|:..||...|:| :.:.
Worm   276 YRECKLVHADLSEFNMLVHDGKLWIIDVSQSVEQDHPHALEFLRMDCNNVNKFFRELGVP-VLSV 339

  Fly   497 EQLFEFITG---LNSEVHTAAQLEQIHTRGASIS---QATAPNQEECPDELKPLEY--PFELAWE 553
            .:|||.|..   .:.|:.|..:.|::.......|   .|..|::         ||:  .||...:
Worm   340 RRLFEVIVDPLMSSKEMETIIEEERVLVNSEDDSLFMNAFIPHK---------LEHVLHFERDGK 395

  Fly   554 KSQQDRAAQKALQQAQDNNDNKTD--TDKDQETDDNENDSDDKEKINKTA 601
            .:::...|....|......|.|.|  .::..::|||:::.:.|:...|.|
Worm   396 LAKEGVEANNPFQNIVSKIDLKGDGFGEEHDDSDDNDDEENGKKSRKKRA 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3008	NP_608871.1	RIO1	242..505	CDD:224632	115/268 (43%)
CG3008	NP_608871.1	RIO3_euk	278..488	CDD:270697	96/209 (46%)
riok-1	NP_001021570.2	RIO1	98..334	CDD:224632	110/257 (43%)
riok-1	NP_001021570.2	RIO1_euk	144..330	CDD:270698	95/207 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1238900at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920