DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cf2 and YPR015C

DIOPT Version :9

Sequence 1:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_015340.1	Gene:	YPR015C / 856125	SGDID:	S000006219	Length:	247	Species:	Saccharomyces cerevisiae

Alignment Length:	193	Identity:	53/193 - (27%)
Similarity:	82/193 - (42%)	Gaps:	40/193 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   291 PLTVKLNKNANGGAIVSHPQVIIKEEPLSLSDSGDVV-----NSV---PVYA---------IQAN 338
            |||.::|:.|       .|.......|.||..:.|.|     ||:   ||.|         ::..
Yeast    53 PLTPEINQAA-------LPPPAYHYAPSSLHQTEDPVWRSSPNSIIFSPVIATPQPFPLTFVERQ 110

  Fly   339 PGVPAPASSGVLVGTQTVPADLAH-------KIRHKCPDCPKTF--KTPGTLAMHRK----IHTG 390
            ...|..:::......|:||..:.|       .:.::....|...  :.||||....:    :...
Yeast   111 SCCPIYSTAASSYTAQSVPPSMQHFQEENHRAVSNEQYSLPNVHIGQNPGTLLSQTQTDLDLIQK 175

  Fly   391 EADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFHC--GYCEKSFSVKDYLTKHIRTH 451
            :..|..|.|. .|..|||..::.:||:.|..||||:.||.|  .:|.|||:||..:.:|:|||
Yeast   176 QLRAVVKLRK-QCPICGKVCSRPSTLRTHYLIHTGDTPFKCTWEHCNKSFNVKSNMLRHLRTH 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	32/94 (34%)
		C2H2 Zn finger	368..388	CDD:275368	5/25 (20%)
		C2H2 Zn finger	403..423	CDD:275368	7/19 (37%)
		C2H2 Zn finger	431..451	CDD:275368	9/21 (43%)
		zf-H2C2_2	443..468	CDD:316026	4/9 (44%)
		C2H2 Zn finger	459..480	CDD:275368
YPR015C	NP_015340.1	COG5048	<17..247	CDD:227381	53/193 (27%)
		C2H2 Zn finger	187..207	CDD:275370	7/19 (37%)
		C2H2 Zn finger	215..237	CDD:275370	9/21 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050