DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cf2 and SCRT2

DIOPT Version :9

Sequence 1:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_149120.1	Gene:	SCRT2 / 85508	HGNCID:	15952	Length:	307	Species:	Homo sapiens

Alignment Length:	172	Identity:	54/172 - (31%)
Similarity:	76/172 - (44%)	Gaps:	40/172 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   365 RHKCPDCPKTFKTPGTLAMHRKIHTGEADATPKERP----------------------YTCSYCG 407
            ||.|.:|.||:.|...|:.|::.|........::.|                      :.|..||
Human   154 RHACAECGKTYATSSNLSRHKQTHRSLDSQLARKCPTCGKAYVSMPALAMHLLTHNLRHKCGVCG 218

  Fly   408 KSFTQSNTLKQHTRIHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSAL 472
            |:|::...|:.|.|.|||||||.|.:|.|:|:.:..|..|::||:..|.|.|..|||.|..:|.|
Human   219 KAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHYRCRQCDKSFALKSYL 283

  Fly   473 TVHTTKLHPLXGRPGGGRQLPVPAPAAPPPPTHPPNPSGPGA 514
            ..|..               ...|.||.||   ||.|:||.:
Human   284 HKHCE---------------AACAKAAEPP---PPTPAGPAS 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	41/128 (32%)
		C2H2 Zn finger	368..388	CDD:275368	7/19 (37%)
		C2H2 Zn finger	403..423	CDD:275368	8/19 (42%)
		C2H2 Zn finger	431..451	CDD:275368	6/19 (32%)
		zf-H2C2_2	443..468	CDD:316026	11/24 (46%)
		C2H2 Zn finger	459..480	CDD:275368	8/20 (40%)
SCRT2	NP_149120.1	SNAG domain. /evidence=ECO:0000250	1..20
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	34..90
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..148
		C2H2 Zn finger	157..177	CDD:275368	7/19 (37%)
		COG5048	<210..>277	CDD:227381	29/66 (44%)
		C2H2 Zn finger	214..234	CDD:275368	8/19 (42%)
		zf-H2C2_2	227..250	CDD:290200	13/22 (59%)
		C2H2 Zn finger	242..262	CDD:275368	6/19 (32%)
		zf-H2C2_2	254..278	CDD:290200	10/23 (43%)
		C2H2 Zn finger	270..286	CDD:275368	7/15 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910