Protein Alignment Cf2 and ZNF165

DIOPT Version :10

• Sequence 1: NP_001350854.1
• Gene: Cf2 / 33692
• FlyBaseID: FBgn0000286
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_003438.1
• Gene: ZNF165 / 7718
• HGNCID: 12953
• Length: 485
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 94/421 - (22%)
• Similarity: 139/421 - (33%)
• Gaps: 187/421 - (44%)

  Fly   229 QQLQAEHHHQQQ----------------------HQQQQQQQQQQQELLEQQQREMQEQAQQQQV 271
            |.|:.|.|.::|                      |:...:..::...:||..:|...|...|.|.
Human    76 QWLKPEIHTKEQILELLVLEQFLTILPGDLQAWVHEHYPESGEEAVTILEDLERGTDEAVLQVQA 140

  Fly   272 HHHQQDQDLAGDQVALKVPPLTVKL---------------------------------------- 296
            |.|  .|::...:|:...|.|.|||
Human   141 HEH--GQEIFQKKVSPPGPALNVKLQPVETKAHFDSSEPQLLWDCDNESENSRSMPKLEIFEKIE 203

  Fly   297 ---------------------------------------------------------NKNANGGA 304
                                                                     :||...|.
Human   204 SQRIISGRISGYISEASGESQDICKSAGRVKRQWEKESGESQRLSSAQDEGFGKILTHKNTVRGE 268

  Fly   305 IVSHPQVIIKEEPLSLSD--------------------SGDVVNSVPVYAIQAN---------PG 340
            |:||...   |..|:|:.                    :.|.:|...:||.:.|         |.
Human   269 IISHDGC---ERRLNLNSNEFTHQKSCKHGTCDQSFKWNSDFINHQIIYAGEKNHQYGKSFKSPK 330

  Fly   341 VPAPASSGVLVGTQTVPADLAHKIRHKCPDCPKTFKTPGTLAMHRKIHTGE-------------- 391
            :...|:  |..|.:|          |:|.:|.|.|:....||.|::|||||
Human   331 LAKHAA--VFSGDKT----------HQCNECGKAFRHSSKLARHQRIHTGERCYECNECGKSFAE 383

  Fly   392 -ADAT------PKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFHCGYCEKSFSVKDYLTKHIR 449
             :|.|      ..|||:.|..||::|..::.|.:|.||||.|||:.|..|.|:|.|..:|.:|.|
Human   384 SSDLTRHRRIHTGERPFGCKECGRAFNLNSHLIRHQRIHTREKPYECSECGKTFRVSSHLIRHFR 448

  Fly   450 THTGEKPYTCPYCDKRFTQRSALTVHTTKLH 480
            .|||||||.|..|.:.|:|.|.|:.| .::|
Human   449 IHTGEKPYECSECGRAFSQSSNLSQH-QRIH 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	51/127 (40%)
		C2H2 Zn finger	368..388	CDD:275368	7/19 (37%)
		C2H2 Zn finger	403..423	CDD:275368	7/19 (37%)
		C2H2 Zn finger	431..451	CDD:275368	8/19 (42%)
		zf-H2C2_2	443..468	CDD:463886	13/24 (54%)
		C2H2 Zn finger	459..480	CDD:275368	7/20 (35%)
ZNF165	NP_003438.1	SCAN	45..157	CDD:128708	16/82 (20%)
		C2H2 Zn finger	297..314	CDD:275368	2/16 (13%)
		zf-C2H2	344..366	CDD:395048	8/21 (38%)
		C2H2 Zn finger	346..366	CDD:275368	7/19 (37%)
		COG5048	370..>431	CDD:227381	18/60 (30%)
		zf-C2H2	372..394	CDD:395048	2/21 (10%)
		C2H2 Zn finger	374..394	CDD:275368	2/19 (11%)
		C2H2 Zn finger	402..422	CDD:275368	7/19 (37%)
		COG5048	426..>479	CDD:227381	25/54 (46%)
		C2H2 Zn finger	430..450	CDD:275368	8/19 (42%)
		C2H2 Zn finger	458..478	CDD:275368	7/20 (35%)