DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cf2 and zgc:165514

DIOPT Version :9

Sequence 1:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001092705.1	Gene:	zgc:165514 / 449909	ZFINID:	ZDB-GENE-041008-169	Length:	298	Species:	Danio rerio

Alignment Length:	246	Identity:	72/246 - (29%)
Similarity:	109/246 - (44%)	Gaps:	49/246 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 HHHQQQHQQQQQQQQQQQELLEQQQREMQEQAQQQQVHHHQQDQDLAGDQVALKVPPLTVKLNKN 299
            |...::|..|.:..:|:::|.|::.::     :.:..|.|             ..|.......:.
Zfish    11 HEDAEEHTDQMEVNEQREDLNEEKDKQ-----RTKTTHLH-------------SCPQCGKSFRRK 57

  Fly   300 ANGGAIVSHPQVIIKEEPLSLSDSGDVVNSVPVYAIQANPGVPAPASSGVLVGTQTVPADLAHKI 364
            ||   :..|.:....|:|.:.::.|...:.:..|...                 |....|   |.
Zfish    58 AN---LNMHRKTHAGEKPYTCTECGKSFSQLNNYKQH-----------------QKTHED---KR 99

  Fly   365 RHKCPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPF 429
            .|.|..|.|:|...|.|..|:.||||       |:|:.||||.|||::|..|:.|.|||||||||
Zfish   100 DHDCLQCGKSFTRAGGLKRHQMIHTG-------EKPHKCSYCEKSFSRSGHLRVHERIHTGEKPF 157

  Fly   430 HCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVHTTKLH 480
            .|..|...|.:...|.:|:|.||.||||.|.:|:|||::.:....| .|.|
Zfish   158 TCTQCGHDFRLSSDLKQHMRIHTNEKPYACLFCEKRFSRLAHCKQH-QKTH 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	50/106 (47%)
		C2H2 Zn finger	368..388	CDD:275368	7/19 (37%)
		C2H2 Zn finger	403..423	CDD:275368	11/19 (58%)
		C2H2 Zn finger	431..451	CDD:275368	6/19 (32%)
		zf-H2C2_2	443..468	CDD:316026	14/24 (58%)
		C2H2 Zn finger	459..480	CDD:275368	7/20 (35%)
zgc:165514	NP_001092705.1	C2H2 Zn finger	47..67	CDD:275368	4/22 (18%)
		zf-H2C2_2	59..84	CDD:290200	5/27 (19%)
		COG5048	<71..259	CDD:227381	59/165 (36%)
		C2H2 Zn finger	75..95	CDD:275368	3/36 (8%)
		C2H2 Zn finger	103..123	CDD:275368	7/19 (37%)
		zf-H2C2_2	116..140	CDD:290200	15/30 (50%)
		C2H2 Zn finger	131..151	CDD:275368	11/19 (58%)
		C2H2 Zn finger	159..179	CDD:275368	6/19 (32%)
		zf-H2C2_2	171..196	CDD:290200	14/24 (58%)
		C2H2 Zn finger	187..207	CDD:275368	7/20 (35%)
		C2H2 Zn finger	215..235	CDD:275368
		zf-H2C2_2	227..250	CDD:290200
		C2H2 Zn finger	243..263	CDD:275368
		C2H2 Zn finger	271..289	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100