DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cf2 and sqz

DIOPT Version :9

Sequence 1:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster

Alignment Length:	243	Identity:	79/243 - (32%)
Similarity:	104/243 - (42%)	Gaps:	54/243 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 QQQQQELLEQQQREMQEQAQQQQVHHHQQDQDLAGDQVALKVPPLTVKLNKNANGGAIVSHPQVI 312
            |.|||.::|||..  .:|.|||.:||.||.|.          || .:|::.:|.......|.|..
  Fly    65 QHQQQMVMEQQPH--PDQQQQQHLHHPQQQQH----------PP-QLKVSYSAPNSPPTPHEQQE 116

  Fly   313 IKEEP---------LSLSDSGDVVNSVPVYAIQANPGVPAPAS-SGVLVGTQTVPADLAHKIRHK 367
            .|.:|         .|.|.||            :|...|...| .|  .|.|..|        :|
  Fly   117 QKYDPNRSPPRQQMSSASGSG------------SNGSSPEEESRRG--DGDQAKP--------YK 159

  Fly   368 CPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFHCG 432
            |..|.|:|.....|:.|.:||.|       .:||.|..|.:.|||.:.|:||.|.|||:||:.|.
  Fly   160 CGSCSKSFANSSYLSQHTRIHLG-------IKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCR 217

  Fly   433 Y--CEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVHTTK 478
            :  |.|:||....|..|.|.|..:||:.|..|.|.|:....|..|..|
  Fly   218 HAGCPKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFSDEMTLLEHIPK 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	41/108 (38%)
		C2H2 Zn finger	368..388	CDD:275368	6/19 (32%)
		C2H2 Zn finger	403..423	CDD:275368	9/19 (47%)
		C2H2 Zn finger	431..451	CDD:275368	8/21 (38%)
		zf-H2C2_2	443..468	CDD:316026	10/24 (42%)
		C2H2 Zn finger	459..480	CDD:275368	7/20 (35%)
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	6/19 (32%)
		zf-H2C2_2	172..197	CDD:290200	10/31 (32%)
		zf-C2H2	186..208	CDD:278523	10/21 (48%)
		C2H2 Zn finger	188..208	CDD:275368	9/19 (47%)
		zf-C2H2_8	191..271	CDD:292531	31/75 (41%)
		zf-H2C2_2	200..227	CDD:290200	13/26 (50%)
		C2H2 Zn finger	216..238	CDD:275368	8/21 (38%)
		C2H2 Zn finger	246..266	CDD:275368	7/20 (35%)
		C2H2 Zn finger	277..297	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457131
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840