DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cf2 and CG8159

DIOPT Version :9

Sequence 1:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	346	Identity:	83/346 - (23%)
Similarity:	123/346 - (35%)	Gaps:	109/346 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 QQQELLEQQQREMQEQAQQQQVHHHQQDQDLAGDQVALKVP--PLTVKLNKNANGGAIVSHPQVI 312
            :.|::.|:.....:|...:..|....:.|....:..|.|.|  ||                 :|:
  Fly    71 RSQKIFEESLVRNEEDTFRSSVRRSARSQRQRHEDTAPKTPASPL-----------------EVM 118

  Fly   313 IKEEPLSLSDSG-------DVVNSVPV-YAIQA------NPGVPAPA------SSGVLVGTQ--- 354
            ||.|.||..|..       |..|...: .||:|      :.|..:|.      ..|:..|.:
  Fly   119 IKLESLSNGDEEDDGIDHLDSCNEADMELAIKAMSSSTEDDGTTSPVRLKRTRRRGLKKGGKGEN 183

  Fly   355 ----TVPADLA---------------HKIRH------KCPDCPKTFKTPGTLAMHRKIHTGEADA 394
                |:|....               |..:|      :|..||..|.:.|.|..|:.:|||
  Fly   184 RTKVTLPVFFCDQCGNNITGKSSFDRHLRKHSGIRPFQCELCPARFLSSGELKGHQVMHTG---- 244

  Fly   395 TPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTC 459
               :|.:.|.||.:::...:...:|.|.||.::||.|..|.|||:....|..|:..||||:.:.|
  Fly   245 ---DRKFQCRYCDRTYVNYSGRLRHERTHTNDRPFICAQCGKSFTNSYILKNHMLIHTGERLFRC 306

  Fly   460 PYCDKRFTQRSALTVH---TTKLHPL--XGRPGGGRQLPVPAPAAPPPPTHPPNPSGPGAPPPLS 519
            ..|.:.|.:.:.|..|   .|..|.|   ....||.||                      .|..|
  Fly   307 ELCHRSFARPTHLKTHFRSNTHKHNLEKSMADAGGVQL----------------------SPSQS 349

  Fly   520 AD-----TDTDPKKPSAAAAA 535
            ||     |:   |:|.|.|.|
  Fly   350 ADQVKFVTE---KEPEAEADA 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	35/112 (31%)
		C2H2 Zn finger	368..388	CDD:275368	7/19 (37%)
		C2H2 Zn finger	403..423	CDD:275368	5/19 (26%)
		C2H2 Zn finger	431..451	CDD:275368	7/19 (37%)
		zf-H2C2_2	443..468	CDD:316026	9/24 (38%)
		C2H2 Zn finger	459..480	CDD:275368	6/23 (26%)
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	1/6 (17%)
		C2H2 Zn finger	194..214	CDD:275368	1/19 (5%)
		COG5048	<197..322	CDD:227381	37/131 (28%)
		zf-H2C2_2	206..231	CDD:290200	6/24 (25%)
		C2H2 Zn finger	222..242	CDD:275368	7/19 (37%)
		C2H2 Zn finger	250..270	CDD:275368	5/19 (26%)
		zf-H2C2_2	265..287	CDD:290200	11/21 (52%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		zf-H2C2_2	291..315	CDD:290200	9/23 (39%)
		C2H2 Zn finger	306..328	CDD:275368	5/21 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010