DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cf2 and CG14655

DIOPT Version :9

Sequence 1:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_649494.1	Gene:	CG14655 / 40594	FlyBaseID:	FBgn0037275	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	448	Identity:	111/448 - (24%)
Similarity:	171/448 - (38%)	Gaps:	126/448 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 CPMCHQQFERPQHVADHMQLCHGITLNAQGAIATLDGGHPQAQQHPKLSHPCFNCDEKFGNAVDL 140
            ||:|                    .:.:.|:|..|.....:|...| |:.|..||.|.|   :.|
  Fly     8 CPLC--------------------AVPSFGSIDALQQRLIKAANGP-LACPFANCKELF---LGL 48

  Fly   141 DE--HHRLAHQTPAFLSRCLMCSIYGIHSATQQPNEYKCTQCGSICTTAMLAAGQQGFMEQQEAA 203
            |:  .|..:|.:       ||........|..||                  |..:||:    ||
  Fly    49 DKLTIHLFSHTS-------LMAQEGNESPANGQP------------------ASSRGFL----AA 84

  Fly   204 VTPDDQL------PAM-APRDMRLTP-------EEQHHQQQLQAEHHHQQQHQQQQQQQQQQQEL 254
            ..|..:.      |.: .|..:|.||       |......:|: :.|.:..|:..:.:.:|:
  Fly    85 APPKRRAKRTRSKPVVPTPPPVRTTPPAHCDICEFSFRNTELR-DMHVRLVHENAEGEPKQK--- 145

  Fly   255 LEQQQREMQEQAQQQQVHHHQQDQDLAGD-QVALK------VPPLTVKLNKN------ANGGAIV 306
             |.||:|..:  :..:.|...:...:.|. ::.||      ||......|.|      :...|:.
  Fly   146 -EPQQKEPDQ--EPYKCHLCSKTFRMKGSLRIHLKVVHMMGVPCSNPNPNPNPSPTPASTTSAVT 207

  Fly   307 SHPQVIIKE-----EPLSLSDSGD--VVNSVPVYA-------IQANPGVPAPASSGVLVGTQTVP 357
            :.|::.|.:     ||.:|.:..:  ...|.| ||       :|.:|..|..       ||.|..
  Fly   208 ATPKLSICDRIRHTEPGALGNGNNSTCTASQP-YALSGALSMLQQSPSSPES-------GTATPK 264

  Fly   358 ADLAHKIRHKCPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRI 422
            .       .:|..|.|:|.|...|..|:::|||       |.||||..|.::||...:..:|...
  Fly   265 L-------WECDVCSKSFTTKYFLKKHKRLHTG-------EMPYTCEICARTFTFQQSYHKHLLY 315

  Fly   423 HTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVHTTKLH 480
            |:..||..||.|.::|.....|..|.|.|:||||:.|..|.|.|.||.:..|| |::|
  Fly   316 HSEVKPHVCGVCGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSFLVH-TRIH 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	40/106 (38%)
		C2H2 Zn finger	368..388	CDD:275368	7/19 (37%)
		C2H2 Zn finger	403..423	CDD:275368	5/19 (26%)
		C2H2 Zn finger	431..451	CDD:275368	7/19 (37%)
		zf-H2C2_2	443..468	CDD:316026	12/24 (50%)
		C2H2 Zn finger	459..480	CDD:275368	9/20 (45%)
CG14655	NP_649494.1	C2H2 Zn finger	268..288	CDD:275368	7/19 (37%)
		zf-H2C2_2	281..304	CDD:290200	11/29 (38%)
		C2H2 Zn finger	324..344	CDD:275368	7/19 (37%)
		zf-H2C2_2	339..361	CDD:290200	11/21 (52%)
		C2H2 Zn finger	352..372	CDD:275368	9/20 (45%)
		zf-H2C2_2	364..389	CDD:290200	4/10 (40%)
		C2H2 Zn finger	380..396	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050