DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cf2 and Aef1

DIOPT Version :9

Sequence 1:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001262157.1	Gene:	Aef1 / 40370	FlyBaseID:	FBgn0005694	Length:	454	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	91/314 - (28%)
Similarity:	128/314 - (40%)	Gaps:	75/314 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 AVTPDDQLPAMAPRDMRLTPEEQHHQQQLQAEHHHQQQHQQQQQQQQQQQELLEQQQREMQEQAQ 267
            |::.:..:..:|.:.........:::...||.|.......||||||||                |
  Fly    16 AMSSNCDIVIVAAQPQTTIANNNNNETVTQATHPAHMAAVQQQQQQQQ----------------Q 64

  Fly   268 QQQVHHHQQDQDLAGDQVALKVPP---------------LTVKLNKNANGGAI------------ 305
            |||.||.||.|..:|..   .|||               ::.:.:..|...|:
  Fly    65 QQQQHHQQQQQQSSGPP---SVPPPPTELPLPFQMHLSGISAEAHSAAQAAAMAAAQAAAAQAAA 126

  Fly   306 ---------VSHPQVIIKEEPLSLSDSGDVVNSVPVYAIQANPGVPAPASSGVLVGTQTVPADLA 361
                     .||...:....|.::.....:.|....:..:.|      |:.|| .|....|....
  Fly   127 AEQQQPPPPTSHLTHLTTHSPTTIHSEHYLANGHSEHPGEGN------AAVGV-GGAVREPEKPF 184

  Fly   362 HKIRHKCPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGE 426
            |     |..|.:.|:...||..|.|||||       |:||.|:.|.|:|.||:||..|.:|||||
  Fly   185 H-----CTVCDRRFRQLSTLTNHVKIHTG-------EKPYKCNVCDKTFRQSSTLTNHLKIHTGE 237

  Fly   427 KPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVHTTKLH 480
            ||::|.:|.|.|.....|..|::.||||||:.|..|.|:|.|.|.|..| .|:|
  Fly   238 KPYNCNFCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNH-IKIH 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	48/106 (45%)
		C2H2 Zn finger	368..388	CDD:275368	7/19 (37%)
		C2H2 Zn finger	403..423	CDD:275368	9/19 (47%)
		C2H2 Zn finger	431..451	CDD:275368	6/19 (32%)
		zf-H2C2_2	443..468	CDD:316026	12/24 (50%)
		C2H2 Zn finger	459..480	CDD:275368	9/20 (45%)
Aef1	NP_001262157.1	C2H2 Zn finger	186..206	CDD:275368	7/19 (37%)
		zf-H2C2_2	199..223	CDD:290200	14/30 (47%)
		C2H2 Zn finger	214..234	CDD:275368	9/19 (47%)
		zf-H2C2_2	227..251	CDD:290200	13/23 (57%)
		C2H2 Zn finger	242..262	CDD:275368	6/19 (32%)
		zf-H2C2_2	255..279	CDD:290200	12/23 (52%)
		C2H2 Zn finger	270..290	CDD:275368	9/20 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050