DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cf2 and CG12605

DIOPT Version :9

Sequence 1:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001261387.1	Gene:	CG12605 / 38468	FlyBaseID:	FBgn0035481	Length:	619	Species:	Drosophila melanogaster

Alignment Length:	276	Identity:	76/276 - (27%)
Similarity:	118/276 - (42%)	Gaps:	47/276 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 LTPEEQHHQQQL------QAEHHHQQQHQQQQQQQQQQQELLEQQQREMQEQAQQQQVHH-HQQD 277
            |||....|...:      .:|...||..:...||.||:...|:.....:..:.:..:... .:||
  Fly   322 LTPPNSDHSSDVDIDMSSSSESGLQQWGKPNPQQNQQRASALKMCLNMLDGRTKASKAAAVTKQD 386

  Fly   278 QDLAGDQVALKVPPLTVKLNKNANGGAIVSHPQVIIKEEP---LSLSDSGDVVNSVPVYAIQANP 339
            :     |..::..|.:.:.|.::.||.....|     |.|   |..|.||:..|    || :...
  Fly   387 R-----QEPMQPRPKSAQSNASSGGGPPSEPP-----ENPAASLGHSSSGNGEN----YA-KRKR 436

  Fly   340 GVPAPASSGVLVGTQTVPADLA-HKIRH---------KCPDCPKTFKTPGTLAMHRKIHTGEADA 394
            |.......|....|.   ::|: ||..|         ||..|.|.:.:...||||...|
  Fly   437 GCYKCCECGKQYATS---SNLSRHKQTHRSLDSQSAKKCNTCGKAYVSMPALAMHLLTH------ 492

  Fly   395 TPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTC 459
               :..::|..|||.|::...|:.|.|.||||||:.|.:|.|:|:.:..|..|::||:|:|.:.|
  Fly   493 ---KLSHSCDICGKLFSRPWLLQGHLRSHTGEKPYACVHCGKAFADRSNLRAHMQTHSGDKNFKC 554

  Fly   460 PYCDKRFTQRSALTVH 475
            ..|:|.|..:|.|..|
  Fly   555 HRCNKTFALKSYLNKH 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	39/115 (34%)
		C2H2 Zn finger	368..388	CDD:275368	7/19 (37%)
		C2H2 Zn finger	403..423	CDD:275368	8/19 (42%)
		C2H2 Zn finger	431..451	CDD:275368	6/19 (32%)
		zf-H2C2_2	443..468	CDD:316026	10/24 (42%)
		C2H2 Zn finger	459..480	CDD:275368	7/17 (41%)
CG12605	NP_001261387.1	zf-C2H2	439..461	CDD:278523	5/24 (21%)
		C2H2 Zn finger	441..461	CDD:275370	5/22 (23%)
		C2H2 Zn finger	472..492	CDD:275368	7/19 (37%)
		COG5048	492..>570	CDD:227381	31/86 (36%)
		zf-C2H2	496..518	CDD:278523	8/21 (38%)
		C2H2 Zn finger	498..518	CDD:275368	8/19 (42%)
		zf-H2C2_2	511..534	CDD:290200	12/22 (55%)
		zf-C2H2	524..546	CDD:278523	6/21 (29%)
		C2H2 Zn finger	526..546	CDD:275368	6/19 (32%)
		zf-H2C2_2	538..562	CDD:290200	9/23 (39%)
		C2H2 Zn finger	554..571	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457105
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840