DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cf2 and Zfp521

DIOPT Version :9

Sequence 1:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	XP_038952847.1	Gene:	Zfp521 / 307579	RGDID:	1307345	Length:	1321	Species:	Rattus norvegicus

Alignment Length:	192	Identity:	56/192 - (29%)
Similarity:	85/192 - (44%)	Gaps:	33/192 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   319 SLSDSGDVVNSVPVYAIQANPGVPA--------PASSGVLVGTQTVPA-----DLAHK-----IR 365
            ||||    :....::..|...||..        |||| .....||.|:     |...:     :.
  Rat    58 SLSD----ITEHKIHQCQLTDGVDVEDDPTCSWPASS-PSSKDQTSPSHGEGCDFGEEEGGPGLP 117

  Fly   366 HKCPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIHTGEKPFH 430
            :.|..|.|:|.....|..|.:.|:.:.       |:.|:||.:.|....:..:|.::|||:|.:|
  Rat   118 YPCQFCDKSFSRLSYLKHHEQSHSDKL-------PFKCTYCSRLFKHKRSRDRHIKLHTGDKKYH 175

  Fly   431 CGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVHTTKLHPLX--GRPGGGR 490
            |..|:.:||..|:|..|::|||..|||.|..|.:.|...|:|..| .::|..   |...|.|
  Rat   176 CSECDAAFSRSDHLKIHLKTHTSNKPYKCAVCRRGFLSSSSLHGH-MQVHERSKDGSQSGSR 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	35/106 (33%)
		C2H2 Zn finger	368..388	CDD:275368	6/19 (32%)
		C2H2 Zn finger	403..423	CDD:275368	5/19 (26%)
		C2H2 Zn finger	431..451	CDD:275368	7/19 (37%)
		zf-H2C2_2	443..468	CDD:316026	11/24 (46%)
		C2H2 Zn finger	459..480	CDD:275368	6/20 (30%)
Zfp521	XP_038952847.1	COG5048	<84..236	CDD:227381	48/160 (30%)
		C2H2 Zn finger	120..140	CDD:275368	6/19 (32%)
		C2H2 Zn finger	148..168	CDD:275368	5/19 (26%)
		C2H2 Zn finger	176..196	CDD:275368	7/19 (37%)
		C2H2 Zn finger	204..224	CDD:275368	6/20 (30%)
		C2H2 Zn finger	312..332	CDD:275368
		C2H2 Zn finger	407..428	CDD:275368
		C2H2 Zn finger	439..460	CDD:275368
		C2H2 Zn finger	479..498	CDD:275368
		C2H2 Zn finger	636..656	CDD:275368
		C2H2 Zn finger	666..686	CDD:275368
		C2H2 Zn finger	696..713	CDD:275368
		C2H2 Zn finger	724..745	CDD:275368
		C2H2 Zn finger	754..774	CDD:275368
		COG5236	785..>964	CDD:227561
		C2H2 Zn finger	785..805	CDD:275368
		C2H2 Zn finger	811..829	CDD:275368
		C2H2 Zn finger	888..909	CDD:275368
		C2H2 Zn finger	932..952	CDD:275368
		C2H2 Zn finger	961..981	CDD:275368
		C2H2 Zn finger	1228..1248	CDD:275368
		C2H2 Zn finger	1259..1280	CDD:275368
		C2H2 Zn finger	1289..1305	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100