DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cf2 and Zfp280b

DIOPT Version :9

Sequence 1:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001099854.1	Gene:	Zfp280b / 294343	RGDID:	1565460	Length:	532	Species:	Rattus norvegicus

Alignment Length:	217	Identity:	59/217 - (27%)
Similarity:	81/217 - (37%)	Gaps:	42/217 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   286 ALKVPPLTVKLNKNANGGAIVS---HPQVIIKEEPLSLSDSGDVVNSVPVYAIQANPGV--PAPA 345
            :|:.|.   .||...||..:..   ||:          .|||.|...   ::..|:|..  |...
  Rat   219 SLEAPK---SLNLFVNGAPLSGDPVHPR----------QDSGSVDTD---FSSLASPETFDPKKG 267

  Fly   346 SSGVLVGT--------QTVPADLAHKIRHKCPDCPKTFKTPGTLAMHRKIH-----TGEADATPK 397
            |..:|:..        :..|....| ...|||.|.|..|.. ....|.|.|     .|..:|.
  Rat   268 SLTLLLSDFYYGQYKGEGKPEQKTH-TTFKCPSCSKALKNV-KFMNHTKHHLELERQGSDEAW-- 328

  Fly   398 ERPYTCSYCGKSFTQSNTLKQH-TRIHTGEKP-FHCGYCEKSFSVKDYLTKHIRTH--TGEKPYT 458
            |...||..|.:.|.....|:.| .|:||...| ..|..||.||..:..|.:|::.:  .||.||.
  Rat   329 ESHTTCLRCHRLFASPFQLECHIDRVHTAPDPCVVCKICELSFETEQVLLEHMKDNHKPGEMPYV 393

  Fly   459 CPYCDKRFTQRSALTVHTTKLH 480
            |..|..|.:..:.:..|.||.|
  Rat   394 CQVCKYRSSVFADVETHFTKCH 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	36/115 (31%)
		C2H2 Zn finger	368..388	CDD:275368	7/19 (37%)
		C2H2 Zn finger	403..423	CDD:275368	6/20 (30%)
		C2H2 Zn finger	431..451	CDD:275368	7/19 (37%)
		zf-H2C2_2	443..468	CDD:316026	9/26 (35%)
		C2H2 Zn finger	459..480	CDD:275368	6/20 (30%)
Zfp280b	NP_001099854.1	DUF4195	52..219	CDD:404681	59/217 (27%)
		C2H2 Zn finger	334..355	CDD:275368	6/20 (30%)
		C2H2 Zn finger	364..385	CDD:275368	7/20 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100