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Protein Alignment Cf2 and ZNF497

DIOPT Version :10

Sequence 1:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_940860.2	Gene:	ZNF497 / 162968	HGNCID:	23714	Length:	498	Species:	Homo sapiens

Alignment Length:	469	Identity:	114/469 - (24%)
Similarity:	172/469 - (36%)	Gaps:	141/469 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 VHV--SPHYCPMCHQQFERPQHVADHMQLCHGITLNAQGAIATLDGGHPQAQQHPKLSHP----- 126
            ||.  .|:.||.|.:.|....:::.|.::..|....|..........|.|...|.: :|.
Human   127 VHTGEKPYTCPECGKAFAWSSNLSQHQRIHSGEKPYACRECGKAFRAHSQLIHHQE-THSGLKPF 190

  Fly   127 -CFNCDEKFGNAVDLDEHHRLAHQTPAFLSRCLMCSIYGIHSATQQPNEYKCTQCGSICTTAMLA 190
             |.:|.:.||.:..|.:|.|                   .|:. ::|  |:|.:||.      ..
Human   191 RCPDCGKSFGRSTTLVQHRR-------------------THTG-EKP--YECPECGK------AF 227

  Fly   191 AGQQGFMEQQ--EAAVTPDDQLPAMAPRDMRLTPEEQHHQQQLQAEH------------------ 235
            :....|:|.:  .....|.      |.||.    .:...|....|||
Human   228 SWNSNFLEHRRVHTGARPH------ACRDC----GKAFSQSSNLAEHLKIHAGARPHACPDCGKA 282

  Fly   236 --------HHQQQHQQQQQQQQQQQELLEQQQREMQEQAQQQQVHHHQQDQDLA--GDQVALKVP 290
                    .|::.|..::.....:   ..:..||..:..|.|:.|..::..:.|  |....:
Human   283 FVRVAGLRQHRRTHSSEKPFPCAE---CGKAFRESSQLLQHQRTHTGERPFECAECGQAFVM--- 341

  Fly   291 PLTVKLNKNANGGAIVSHPQVIIKEEPLSLSDSGDVVNSVPVYAIQANPGVPAPASSGVLVGTQT 355
                       |..:..|.:|...|:|.:.:..|      ..::.::|.
Human   342 -----------GSYLAEHRRVHTGEKPHACAQCG------KAFSQRSNL---------------- 373

  Fly   356 VPADLAHKIRHK------CPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSN 414
                |:|:..|.      |.||.|.|:....||.||..|||       |||:.|:.|||:|..|:
Human   374 ----LSHRRTHSGAKPFACADCGKAFRGSSGLAHHRLSHTG-------ERPFACAECGKAFRGSS 427

  Fly   415 TLKQHTRIHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVHTTKL 479
            .|:||.|:|:||:||.|.:|.|:|..|..|..|.||||||:||.|..|.|.|:.|..|..| .|.
Human   428 ELRQHQRLHSGERPFVCAHCSKAFVRKSELLSHRRTHTGERPYACGECGKPFSHRCNLNEH-QKR 491

  Fly   480 HPLXGRPGGGRQLP 493
            |       |||..|
Human   492 H-------GGRAAP 498

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.