Protein Alignment Cf2 and ZNF280B

DIOPT Version :10

• Sequence 1: NP_001350854.1
• Gene: Cf2 / 33692
• FlyBaseID: FBgn0000286
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_542942.2
• Gene: ZNF280B / 140883
• HGNCID: 23022
• Length: 543
• Species: Homo sapiens
• Alignment Length: 206
• Identity: 56/206 - (27%)
• Similarity: 72/206 - (34%)
• Gaps: 51/206 - (24%)

  Fly   368 CPDCPKTFKTPGTLAMH-RKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIH--TGEKPF 429
            |..|.:.|.||..|..| ..:||.:..:|      .|..|..||.....|.||.:.|  .||.|:
Human   345 CQHCHRQFPTPFQLQCHIENVHTAQEPST------VCKICELSFETDQVLLQHMKDHHKPGEMPY 403

  Fly   430 HCGYCEKSFSVKDYLTKHIRT-HTGEKPYTCPYCDKRFTQ-------------RSA--------- 471
            .|..|....||...:..|.|| |...|...||:|.|.|..             :||
Human   404 VCQVCHYRSSVFADVETHFRTCHENTKNLLCPFCLKIFKTATPYMCHYRGHWGKSAHQCSKCRLQ 468

  Fly   472 -LTV-----HTTKLHPLXGRPGGGRQLPVPAPAAPPPPTHPP-----NPSGPGAPPPLSADTDTD 525
             ||.     |.|:.|.: .:|   :||     ...||.|...     .|..||:....|....|.
Human   469 FLTFKEKMEHKTQCHQMFKKP---KQL-----EGLPPETKVTIQVSLEPLQPGSVDVASITVSTS 525

  Fly   526 PKKPSAAAAAS 536
            ..:||...:.|
Human   526 DSEPSLPRSKS 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	37/131 (28%)
		C2H2 Zn finger	368..388	CDD:275368	7/20 (35%)
		C2H2 Zn finger	403..423	CDD:275368	7/19 (37%)
		C2H2 Zn finger	431..451	CDD:275368	7/20 (35%)
		zf-H2C2_2	443..468	CDD:463886	10/25 (40%)
		C2H2 Zn finger	459..480	CDD:275368	11/48 (23%)
ZNF280B	NP_542942.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		DUF4195	45..226	CDD:463993
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	105..138
		C2H2 Zn finger	345..366	CDD:275368	7/20 (35%)
		C2H2 Zn finger	375..395	CDD:275368	7/19 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	518..543		5/19 (26%)