Protein Alignment Cf2 and ZNF280A

DIOPT Version :10

• Sequence 1: NP_001350854.1
• Gene: Cf2 / 33692
• FlyBaseID: FBgn0000286
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_542778.2
• Gene: ZNF280A / 129025
• HGNCID: 18597
• Length: 542
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 48/199 - (24%)
• Similarity: 62/199 - (31%)
• Gaps: 39/199 - (19%)

  Fly   368 CPDCPKTFKTPGTLAMH-RKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIH--TGEKPF 429
            |..|.:.|.||..|..| ..:|.....:.      .|..|..||.....|.||.:.|  .||.|:
Human   336 CQHCHRQFPTPFQLQCHIDSVHIAMGPSA------VCKICELSFETDQVLLQHMKDHHKPGEMPY 394

  Fly   430 HCGYCEKSFSVKDYLTKHIRT-HTGEKPYTCPYCDK-------------RFTQRSALTV------ 474
            .|..|....||...:..|.|| |...|...|.:|.|             |.::|..|..
Human   395 VCQVCHYRSSVFADVETHFRTCHENTKNLLCLFCLKLFKTAIPYMNHCWRHSRRRVLQCSKCRLQ 459

  Fly   475 ---------HTTKLHPLXGRPGGGRQLPVPAPAAPPPPTHPPNPSGPGAPPPLSADTDTDPKKPS 530
                     |.||.|....:|...:.||............ |..||..:....:.|..:.|.|..
Human   460 FLTLKEEIEHKTKDHQTFKKPEQLQGLPSETKVIIQTSVQ-PGSSGMASVIVSNTDPQSSPVKTK 523

  Fly   531 AAAA 534
            ...|
Human   524 KKTA 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	33/121 (27%)
		C2H2 Zn finger	368..388	CDD:275368	7/20 (35%)
		C2H2 Zn finger	403..423	CDD:275368	7/19 (37%)
		C2H2 Zn finger	431..451	CDD:275368	7/20 (35%)
		zf-H2C2_2	443..468	CDD:463886	9/38 (24%)
		C2H2 Zn finger	459..480	CDD:275368	9/48 (19%)
ZNF280A	NP_542778.2	DUF4195	47..217	CDD:463993
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	66..185
		C2H2 Zn finger	336..357	CDD:275368	7/20 (35%)
		C2H2 Zn finger	366..386	CDD:275368	7/19 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	499..542		7/30 (23%)