DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cf2 and ZNF280A

DIOPT Version :9

Sequence 1:NP_001350854.1 Gene:Cf2 / 33692 FlyBaseID:FBgn0000286 Length:537 Species:Drosophila melanogaster
Sequence 2:NP_542778.2 Gene:ZNF280A / 129025 HGNCID:18597 Length:542 Species:Homo sapiens


Alignment Length:199 Identity:48/199 - (24%)
Similarity:62/199 - (31%) Gaps:39/199 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   368 CPDCPKTFKTPGTLAMH-RKIHTGEADATPKERPYTCSYCGKSFTQSNTLKQHTRIH--TGEKPF 429
            |..|.:.|.||..|..| ..:|.....:.      .|..|..||.....|.||.:.|  .||.|:
Human   336 CQHCHRQFPTPFQLQCHIDSVHIAMGPSA------VCKICELSFETDQVLLQHMKDHHKPGEMPY 394

  Fly   430 HCGYCEKSFSVKDYLTKHIRT-HTGEKPYTCPYCDK-------------RFTQRSALTV------ 474
            .|..|....||...:..|.|| |...|...|.:|.|             |.::|..|..      
Human   395 VCQVCHYRSSVFADVETHFRTCHENTKNLLCLFCLKLFKTAIPYMNHCWRHSRRRVLQCSKCRLQ 459

  Fly   475 ---------HTTKLHPLXGRPGGGRQLPVPAPAAPPPPTHPPNPSGPGAPPPLSADTDTDPKKPS 530
                     |.||.|....:|...:.||............ |..||..:....:.|..:.|.|..
Human   460 FLTLKEEIEHKTKDHQTFKKPEQLQGLPSETKVIIQTSVQ-PGSSGMASVIVSNTDPQSSPVKTK 523

  Fly   531 AAAA 534
            ...|
Human   524 KKTA 527

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cf2NP_001350854.1 COG5048 <366..>473 CDD:227381 33/121 (27%)
C2H2 Zn finger 368..388 CDD:275368 7/20 (35%)
C2H2 Zn finger 403..423 CDD:275368 7/19 (37%)
C2H2 Zn finger 431..451 CDD:275368 7/20 (35%)
zf-H2C2_2 443..468 CDD:316026 9/38 (24%)
C2H2 Zn finger 459..480 CDD:275368 9/48 (19%)
ZNF280ANP_542778.2 DUF4195 47..217 CDD:316361
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 105..185
C2H2 Zn finger 336..357 CDD:275368 7/20 (35%)
C2H2 Zn finger 366..386 CDD:275368 7/19 (37%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 502..542 6/26 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24388
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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